Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [29]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 10037-1-Ig - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10037-1-Ig, RRID:AB_2215009
- Product name
- XIAP antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated XIAP antibody (Cat. #10037-1-Ig) is a rabbit polyclonal antibody that shows reactivity with human, rat, mouse and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references VALD-3, a Schiff base ligand synthesized from o-vanillin derivatives, induces cell cycle arrest and apoptosis in breast cancer cells by inhibiting the Wnt/β-catenin pathway.
Cellular FLICE-like inhibitory protein (cFLIP) critically maintains apoptotic resistance in human lens epithelial cells.
Brevilin A Inhibits STAT3 Signaling and Induces ROS-Dependent Apoptosis, Mitochondrial Stress and Endoplasmic Reticulum Stress in MCF-7 Breast Cancer Cells.
miR-431-5p regulates cell proliferation and apoptosis in fibroblast-like synoviocytes in rheumatoid arthritis by targeting XIAP.
Extracellular Vesicle Delivery of TRAIL Eradicates Resistant Tumor Growth in Combination with CDK Inhibition by Dinaciclib.
Effect of epiberberine from Coptis chinensis Franch on inhibition of tumor growth in MKN-45 xenograft mice.
Regorafenib suppresses epidermal growth factor receptor signaling-modulated progression of colorectal cancer.
Synergism of cisplatin-oleanolic acid co-loaded calcium carbonate nanoparticles on hepatocellular carcinoma cells for enhanced apoptosis and reduced hepatotoxicity.
The p300/YY1/miR-500a-5p/HDAC2 signalling axis regulates cell proliferation in human colorectal cancer.
Proscillaridin A Promotes Oxidative Stress and ER Stress, Inhibits STAT3 Activation, and Induces Apoptosis in A549 Lung Adenocarcinoma Cells.
Brevilin A promotes oxidative stress and induces mitochondrial apoptosis in U87 glioblastoma cells.
Anti-breast-Cancer Activity Exerted by β-Sitosterol-d-glucoside from Sweet Potato via Upregulation of MicroRNA-10a and via the PI3K-Akt Signaling Pathway.
An ATM/TRIM37/NEMO Axis Counteracts Genotoxicity by Activating Nuclear-to-Cytoplasmic NF-κB Signaling.
Targeting inhibitors of apoptosis proteins suppresses medulloblastoma cell proliferation via G2/M phase arrest and attenuated neddylation of p21.
PCSK9 regulates apoptosis in human lung adenocarcinoma A549 cells via endoplasmic reticulum stress and mitochondrial signaling pathways.
Phloretin induces apoptosis of human esophageal cancer via a mitochondria-dependent pathway.
Blockade of Inhibitors of Apoptosis Proteins in Combination with Conventional Chemotherapy Leads to Synergistic Antitumor Activity in Medulloblastoma and Cancer Stem-Like Cells.
BG-4, a novel anticancer peptide from bitter gourd (Momordica charantia), promotes apoptosis in human colon cancer cells.
The putative tumor activator ARHGEF3 promotes nasopharyngeal carcinoma cell pathogenesis by inhibiting cellular apoptosis.
PACE4 regulates apoptosis in human prostate cancer cells via endoplasmic reticulum stress and mitochondrial signaling pathways.
CRNDE affects the malignant biological characteristics of human glioma stem cells by negatively regulating miR-186.
Oxaliplatin triggers necrosis as well as apoptosis in gastric cancer SGC-7901 cells.
Trichothecin induces cell death in NF-κB constitutively activated human cancer cells via inhibition of IKKβ phosphorylation.
Overexpression of the truncated form of Livin reveals a complex interaction with caspase-3.
Caspases and inhibitor of apoptosis proteins in cutaneous and mucosal melanoma: expression profile and clinicopathologic significance.
Expression patterns and prognostic significance of inhibitor of apoptosis proteins in adenoid cystic carcinoma and pleomorphic adenoma of lachrymal gland.
Survivin knockdown combined with apoptin overexpression inhibits cell growth significantly.
Apoptosis and proliferation markers in diffusely infiltrating astrocytomas: profiling of 17 molecules.
Survivin nuclear labeling index: a superior biomarker in superficial urothelial carcinoma of human urinary bladder.
Li H, Dang C, Tai X, Xue L, Meng Y, Ma S, Zhang J
Scientific reports 2021 Jul 22;11(1):14985
Scientific reports 2021 Jul 22;11(1):14985
Cellular FLICE-like inhibitory protein (cFLIP) critically maintains apoptotic resistance in human lens epithelial cells.
Huangfu J, Hao C, Wei Z, Wormstone IM, Yan H, Fan X
Cell death & disease 2021 Apr 9;12(4):386
Cell death & disease 2021 Apr 9;12(4):386
Brevilin A Inhibits STAT3 Signaling and Induces ROS-Dependent Apoptosis, Mitochondrial Stress and Endoplasmic Reticulum Stress in MCF-7 Breast Cancer Cells.
Saleem MZ, Nisar MA, Alshwmi M, Din SRU, Gamallat Y, Khan M, Ma T
OncoTargets and therapy 2020;13:435-450
OncoTargets and therapy 2020;13:435-450
miR-431-5p regulates cell proliferation and apoptosis in fibroblast-like synoviocytes in rheumatoid arthritis by targeting XIAP.
Wang Y, Zhang K, Yuan X, Xu N, Zhao S, Hou L, Yang L, Zhang N
Arthritis research & therapy 2020 Oct 6;22(1):231
Arthritis research & therapy 2020 Oct 6;22(1):231
Extracellular Vesicle Delivery of TRAIL Eradicates Resistant Tumor Growth in Combination with CDK Inhibition by Dinaciclib.
Ke C, Hou H, Li J, Su K, Huang C, Lin Y, Lu Z, Du Z, Tan W, Yuan Z
Cancers 2020 May 4;12(5)
Cancers 2020 May 4;12(5)
Effect of epiberberine from Coptis chinensis Franch on inhibition of tumor growth in MKN-45 xenograft mice.
Yu M, Ren L, Liang F, Zhang Y, Jiang L, Ma W, Li C, Li X, Ye X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 May 17;76:153216
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 May 17;76:153216
Regorafenib suppresses epidermal growth factor receptor signaling-modulated progression of colorectal cancer.
Liu YC, Tsai JJ, Weng YS, Hsu FT
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Aug;128:110319
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Aug;128:110319
Synergism of cisplatin-oleanolic acid co-loaded calcium carbonate nanoparticles on hepatocellular carcinoma cells for enhanced apoptosis and reduced hepatotoxicity.
Khan MW, Zhao P, Khan A, Raza F, Raza SM, Sarfraz M, Chen Y, Li M, Yang T, Ma X, Xiang G
International journal of nanomedicine 2019;14:3753-3771
International journal of nanomedicine 2019;14:3753-3771
The p300/YY1/miR-500a-5p/HDAC2 signalling axis regulates cell proliferation in human colorectal cancer.
Tang W, Zhou W, Xiang L, Wu X, Zhang P, Wang J, Liu G, Zhang W, Peng Y, Huang X, Cai J, Bai Y, Bai L, Zhu W, Gu H, Xiong J, Ye C, Li A, Liu S, Wang J
Nature communications 2019 Feb 8;10(1):663
Nature communications 2019 Feb 8;10(1):663
Proscillaridin A Promotes Oxidative Stress and ER Stress, Inhibits STAT3 Activation, and Induces Apoptosis in A549 Lung Adenocarcinoma Cells.
Maryam A, Mehmood T, Yan Q, Li Y, Khan M, Ma T
Oxidative medicine and cellular longevity 2018;2018:3853409
Oxidative medicine and cellular longevity 2018;2018:3853409
Brevilin A promotes oxidative stress and induces mitochondrial apoptosis in U87 glioblastoma cells.
Wang J, Li M, Cui X, Lv D, Jin L, Khan M, Ma T
OncoTargets and therapy 2018;11:7031-7040
OncoTargets and therapy 2018;11:7031-7040
Anti-breast-Cancer Activity Exerted by β-Sitosterol-d-glucoside from Sweet Potato via Upregulation of MicroRNA-10a and via the PI3K-Akt Signaling Pathway.
Xu H, Li Y, Han B, Li Z, Wang B, Jiang P, Zhang J, Ma W, Zhou D, Li X, Ye X
Journal of agricultural and food chemistry 2018 Sep 19;66(37):9704-9718
Journal of agricultural and food chemistry 2018 Sep 19;66(37):9704-9718
An ATM/TRIM37/NEMO Axis Counteracts Genotoxicity by Activating Nuclear-to-Cytoplasmic NF-κB Signaling.
Wu G, Song L, Zhu J, Hu Y, Cao L, Tan Z, Zhang S, Li Z, Li J
Cancer research 2018 Nov 15;78(22):6399-6412
Cancer research 2018 Nov 15;78(22):6399-6412
Targeting inhibitors of apoptosis proteins suppresses medulloblastoma cell proliferation via G2/M phase arrest and attenuated neddylation of p21.
Chen SM, Lin TK, Tseng YY, Tu CH, Lui TN, Huang SF, Hsieh LL, Li YY
Cancer medicine 2018 Aug;7(8):3988-4003
Cancer medicine 2018 Aug;7(8):3988-4003
PCSK9 regulates apoptosis in human lung adenocarcinoma A549 cells via endoplasmic reticulum stress and mitochondrial signaling pathways.
Xu X, Cui Y, Cao L, Zhang Y, Yin Y, Hu X
Experimental and therapeutic medicine 2017 May;13(5):1993-1999
Experimental and therapeutic medicine 2017 May;13(5):1993-1999
Phloretin induces apoptosis of human esophageal cancer via a mitochondria-dependent pathway.
Duan H, Wang R, Yan X, Liu H, Zhang Y, Mu D, Han J, Li X
Oncology letters 2017 Dec;14(6):6763-6768
Oncology letters 2017 Dec;14(6):6763-6768
Blockade of Inhibitors of Apoptosis Proteins in Combination with Conventional Chemotherapy Leads to Synergistic Antitumor Activity in Medulloblastoma and Cancer Stem-Like Cells.
Chen SM, Li YY, Tu CH, Salazar N, Tseng YY, Huang SF, Hsieh LL, Lui TN
PloS one 2016;11(8):e0161299
PloS one 2016;11(8):e0161299
BG-4, a novel anticancer peptide from bitter gourd (Momordica charantia), promotes apoptosis in human colon cancer cells.
Dia VP, Krishnan HB
Scientific reports 2016 Sep 15;6:33532
Scientific reports 2016 Sep 15;6:33532
The putative tumor activator ARHGEF3 promotes nasopharyngeal carcinoma cell pathogenesis by inhibiting cellular apoptosis.
Liu TH, Zheng F, Cai MY, Guo L, Lin HX, Chen JW, Liao YJ, Kung HF, Zeng YX, Xie D
Oncotarget 2016 May 3;7(18):25836-48
Oncotarget 2016 May 3;7(18):25836-48
PACE4 regulates apoptosis in human prostate cancer cells via endoplasmic reticulum stress and mitochondrial signaling pathways.
Yao Z, Sun B, Hong Q, Yan J, Mu D, Li J, Sheng H, Guo H
Drug design, development and therapy 2015;9:5911-23
Drug design, development and therapy 2015;9:5911-23
CRNDE affects the malignant biological characteristics of human glioma stem cells by negatively regulating miR-186.
Zheng J, Li XD, Wang P, Liu XB, Xue YX, Hu Y, Li Z, Li ZQ, Wang ZH, Liu YH
Oncotarget 2015 Sep 22;6(28):25339-55
Oncotarget 2015 Sep 22;6(28):25339-55
Oxaliplatin triggers necrosis as well as apoptosis in gastric cancer SGC-7901 cells.
Wu P, Zhu X, Jin W, Hao S, Liu Q, Zhang L
Biochemical and biophysical research communications 2015 May 1;460(2):183-90
Biochemical and biophysical research communications 2015 May 1;460(2):183-90
Trichothecin induces cell death in NF-κB constitutively activated human cancer cells via inhibition of IKKβ phosphorylation.
Su J, Zhao P, Kong L, Li X, Yan J, Zeng Y, Li Y
PloS one 2013;8(8):e71333
PloS one 2013;8(8):e71333
Overexpression of the truncated form of Livin reveals a complex interaction with caspase-3.
Liu GH, Wang C, Ding ZY
International journal of oncology 2013 Jun;42(6):2037-45
International journal of oncology 2013 Jun;42(6):2037-45
Caspases and inhibitor of apoptosis proteins in cutaneous and mucosal melanoma: expression profile and clinicopathologic significance.
Chen N, Gong J, Chen X, Meng W, Huang Y, Zhao F, Wang L, Zhou Q
Human pathology 2009 Jul;40(7):950-6
Human pathology 2009 Jul;40(7):950-6
Expression patterns and prognostic significance of inhibitor of apoptosis proteins in adenoid cystic carcinoma and pleomorphic adenoma of lachrymal gland.
Liao Y, Zeng H, Wang X, Huang Y, Chen N, Ge B, Tang L, Luo Q
Experimental eye research 2009 Jan;88(1):4-11
Experimental eye research 2009 Jan;88(1):4-11
Survivin knockdown combined with apoptin overexpression inhibits cell growth significantly.
Liu Q, Fu H, Xing R, Tie Y, Zhu J, Sun Z, Zheng X
Cancer biology & therapy 2008 Jul;7(7):1053-60
Cancer biology & therapy 2008 Jul;7(7):1053-60
Apoptosis and proliferation markers in diffusely infiltrating astrocytomas: profiling of 17 molecules.
Liu X, Chen N, Wang X, He Y, Chen X, Huang Y, Yin W, Zhou Q
Journal of neuropathology and experimental neurology 2006 Sep;65(9):905-13
Journal of neuropathology and experimental neurology 2006 Sep;65(9):905-13
Survivin nuclear labeling index: a superior biomarker in superficial urothelial carcinoma of human urinary bladder.
Yin W, Chen N, Zhang Y, Zeng H, Chen X, He Y, Wang X, Zhou Q
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2006 Nov;19(11):1487-97
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2006 Nov;19(11):1487-97
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 10037-1-Ig(XIAP antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of MCF-7 cells, using XIAP antibody 10037-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human pancreas cancer using 10037-1-Ig(XIAP antibody) at dilution of 1:200 (under 40x lens)
- Sample type
- tissue
