CABT-L2221

antibody from Creative Diagnostics

Targeting: XIAP API3, BIRC4, hILP, ILP-1

Western blot (Recommended by provider)

Antibody Data

Product number

CABT-L2221

Provider

Creative Diagnostics

Product name

Rabbit Anti-Human XIAP Polyclonal Antibody

Antibody type

Polyclonal

Description

This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.[provided by RefSeq, Feb 2011]

Reactivity

Human, Porcine

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

200 _g

Concentration

Lot specific

Storage

Avoid repeated freeze/thaw cycles. Store at 4°C for frequent use. Aliquot and store at -20°C for 12 months.