100-401-223

antibody from Rockland Immunochemicals, Inc.

Targeting: GLI1 GLI

Immunocytochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

100-401-223

Provider

Rockland Immunochemicals, Inc.

Proper citation

Rockland Cat#100-401-223, RRID:AB_2111776

Product name

Anti-Gli1 (RABBIT) Antibody - 100-401-223

Antibody type

Polyclonal

Vial size

100 µl

References

Submitted references

Kruppel-Like Factor 4 represses osteoblast differentiation via ciliary Hedgehog signaling.

Takeuchi Y, Kito A, Itoh S, Naruse H, Fujikawa J, Sadek KM, Akiyama S, Yamashiro T, Wakisaka S, Abe M
Experimental cell research 2018 Oct 15;371(2):417-425

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Epigenomic study identifies a novel mesenchyme homeobox2-GLI1 transcription axis involved in cancer drug resistance, overall survival and therapy prognosis in lung cancer patients.

Armas-López L, Piña-Sánchez P, Arrieta O, de Alba EG, Ortiz-Quintero B, Santillán-Doherty P, Christiani DC, Zúñiga J, Ávila-Moreno F
Oncotarget 2017 Sep 15;8(40):67056-67081

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p53 modulates the activity of the GLI1 oncogene through interactions with the shared coactivator TAF9.

Yoon JW, Lamm M, Iannaccone S, Higashiyama N, Leong KF, Iannaccone P, Walterhouse D
DNA repair 2015 Oct;34:9-17

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Targeted disruption of β-arrestin 2-mediated signaling pathways by aptamer chimeras leads to inhibition of leukemic cell growth.

Kotula JW, Sun J, Li M, Pratico ED, Fereshteh MP, Ahrens DP, Sullenger BA, Kovacs JJ
PloS one 2014;9(4):e93441

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NVP-LDE225, a potent and selective SMOOTHENED antagonist reduces melanoma growth in vitro and in vivo.

Jalili A, Mertz KD, Romanov J, Wagner C, Kalthoff F, Stuetz A, Pathria G, Gschaider M, Stingl G, Wagner SN
PloS one 2013;8(7):e69064

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Menin directly represses Gli1 expression independent of canonical Hedgehog signaling.

Gurung B, Feng Z, Hua X
Molecular cancer research : MCR 2013 Oct;11(10):1215-22

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NAV3 copy number changes and target genes in basal and squamous cell cancers.

Maliniemi P, Carlsson E, Kaukola A, Ovaska K, Niiranen K, Saksela O, Jeskanen L, Hautaniemi S, Ranki A
Experimental dermatology 2011 Nov;20(11):926-31

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Defining a role for Sonic hedgehog pathway activation in desmoplastic medulloblastoma by identifying GLI1 target genes.

Yoon JW, Gilbertson R, Iannaccone S, Iannaccone P, Walterhouse D
International journal of cancer 2009 Jan 1;124(1):109-19

Immunocytochemistry

Supportive validation

Submitted by

Rockland Immunochemicals, Inc. (provider)

Main image

Experimental details

Immunohistochemistry using Rockland's anti-Gli-1 antibody shows detection of mouse Gli-1 present in transfected 293T cells (red). HEK293T cells were transiently transfected with Gli-1 (murine). Rockland’s Anti-Gli-1 antiserum (rabbit) was added 1:400, followed by a fluorescent labeled anti-rabbit IgG secondary. Personal communication, Tom Curran, Children’s Hospital of Philadelphia, Philadelphia, PA.

Sample type

IF Microscopy