Antibody data
- Antibody Data
- Antigen structure
- References [28]
- Comments [0]
- Validations [0]
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- Product number
- 66905-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- GLI1 antibody
- Antibody type
- Monoclonal
- Description
- KD/KO validated GLI1 antibody (Cat. #66905-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, rat, mouse and has been validated for the following applications: WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 1D2B2
- Vial size
- 20ul, 150ul
Submitted references Effect of kaempferol on hedgehog signaling pathway in rats with --chronic atrophic gastritis - Based on network pharmacological screening and experimental verification.
Microtubule Stabilization Enhances the Chondrogenesis of Synovial Mesenchymal Stem Cells.
Apatinib Suppresses Gastric Cancer Stem Cells Properties by Inhibiting the Sonic Hedgehog Pathway.
Resveratrol Inhibition of Renal Cancer Stem Cell Characteristics and Modulation of the Sonic Hedgehog Pathway.
Mitochondrial Protection and Against Glutamate Neurotoxicity via Shh/Ptch1 Signaling Pathway to Ameliorate Cognitive Dysfunction by Kaixin San in Multi-Infarct Dementia Rats.
Hedgehog/GLI1 signaling pathway regulates the resistance to cisplatin in human osteosarcoma.
Epigallocatechin-3-gallate inhibits proliferation and triggers apoptosis in colon cancer via the hedgehog/phosphoinositide 3-kinase pathways.
Transcription factor POU4F2 promotes colorectal cancer cell migration and invasion through hedgehog-mediated epithelial-mesenchymal transition.
Disruption of Gprasp2 down-regulates Hedgehog signaling and leads to apoptosis in auditory cells.
Circular RNA circIPO11 drives self-renewal of liver cancer initiating cells via Hedgehog signaling.
ETV4 promotes breast cancer cell stemness by activating glycolysis and CXCR4-mediated sonic Hedgehog signaling.
Identification of a potent antagonist of smoothened in hedgehog signaling.
Meningitic Escherichia coli α-hemolysin aggravates blood-brain barrier disruption via targeting TGFβ1-triggered hedgehog signaling.
Long noncoding RNA LINC00460 promotes the progression of cervical cancer via regulation of the miR-361-3p/Gli1 axis.
Astrocyte-Derived TGFβ1 Facilitates Blood-Brain Barrier Function via Non-Canonical Hedgehog Signaling in Brain Microvascular Endothelial Cells.
Benzidine promotes the stemness of bladder cancer stem cells via activation of the Sonic hedgehog pathway.
Pectin Oligosaccharides Enhance α2,6-Sialylation Modification that Promotes Apoptosis of Bladder Cancer Cells by Targeting the Hedgehog Pathway.
Repair of spinal cord injury in rats via exosomes from bone mesenchymal stem cells requires sonic hedgehog.
Wogonin inhibits the growth of HT144 melanoma via regulating hedgehog signaling-mediated inflammation and glycolysis.
Procyanidin B2 alleviates liver injury caused by cold stimulation through Sonic hedgehog signalling and autophagy.
Rab1A promotes cell proliferation and migration by upregulating Gli1 in colorectal cancer.
Cigarette smoke supports stemness and epithelial-mesenchymal transition in bladder cancer stem cells through SHH signaling.
Liraglutide regulates proliferation, differentiation, and apoptosis of preosteoblasts through a signaling network of Notch/Wnt/Hedgehog signaling pathways.
A Combination of BRD4 and HDAC3 Inhibitors Synergistically Suppresses Glioma Stem Cell Growth by Blocking GLI1/IL6/STAT3 Signaling Axis.
Sonic hedgehog pathway mediates genistein inhibition of renal cancer stem cells.
Genistein inhibits nasopharyngeal cancer stem cells through sonic hedgehog signaling.
TSPAN8 promotes cancer cell stemness via activation of sonic Hedgehog signaling.
Sulforaphane inhibits gastric cancer stem cells via suppressing sonic hedgehog pathway.
Tu W, Hong Y, Huang M, Chen M, Gan H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jan;145:112451
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jan;145:112451
Microtubule Stabilization Enhances the Chondrogenesis of Synovial Mesenchymal Stem Cells.
Li J, Sun Z, Lv Z, Jiang H, Liu A, Wang M, Tan G, Guo H, Sun H, Wu R, Xu X, Yan W, Jiang Q, Ikegawa S, Shi D
Frontiers in cell and developmental biology 2021;9:748804
Frontiers in cell and developmental biology 2021;9:748804
Apatinib Suppresses Gastric Cancer Stem Cells Properties by Inhibiting the Sonic Hedgehog Pathway.
Cao W, Li Y, Sun H, Yang C, Zhu J, Xie C, Li X, Wu J, Geng S, Wang L, Sun L, Geng G, Han H, Zhong C
Frontiers in cell and developmental biology 2021;9:679806
Frontiers in cell and developmental biology 2021;9:679806
Resveratrol Inhibition of Renal Cancer Stem Cell Characteristics and Modulation of the Sonic Hedgehog Pathway.
Sun H, Zhang T, Liu R, Cao W, Zhang Z, Liu Z, Qian W, Wang D, Yu D, Zhong C
Nutrition and cancer 2021;73(7):1157-1167
Nutrition and cancer 2021;73(7):1157-1167
Mitochondrial Protection and Against Glutamate Neurotoxicity via Shh/Ptch1 Signaling Pathway to Ameliorate Cognitive Dysfunction by Kaixin San in Multi-Infarct Dementia Rats.
Li X, Wen W, Li P, Fu Y, Chen H, Wang F, Dai Y, Xu S
Oxidative medicine and cellular longevity 2021;2021:5590745
Oxidative medicine and cellular longevity 2021;2021:5590745
Hedgehog/GLI1 signaling pathway regulates the resistance to cisplatin in human osteosarcoma.
Chen D, Kang X, Li Z, Chen L, Ma Q, Fan P
Journal of Cancer 2021;12(22):6676-6684
Journal of Cancer 2021;12(22):6676-6684
Epigallocatechin-3-gallate inhibits proliferation and triggers apoptosis in colon cancer via the hedgehog/phosphoinositide 3-kinase pathways.
Ding F, Yang S
Canadian journal of physiology and pharmacology 2021 Sep;99(9):910-920
Canadian journal of physiology and pharmacology 2021 Sep;99(9):910-920
Transcription factor POU4F2 promotes colorectal cancer cell migration and invasion through hedgehog-mediated epithelial-mesenchymal transition.
Guo K, Wang P, Zhang L, Zhou Y, Dai X, Yan Y, Chen Y, Wasan HS, Yu J, Ruan S, Sun L
Cancer science 2021 Oct;112(10):4176-4186
Cancer science 2021 Oct;112(10):4176-4186
Disruption of Gprasp2 down-regulates Hedgehog signaling and leads to apoptosis in auditory cells.
Lu Y, Zhang M, Wei Q, Chen Z, Xing G, Yao J, Cao X
Biochemical and biophysical research communications 2021 Oct 15;574:1-7
Biochemical and biophysical research communications 2021 Oct 15;574:1-7
Circular RNA circIPO11 drives self-renewal of liver cancer initiating cells via Hedgehog signaling.
Gu Y, Wang Y, He L, Zhang J, Zhu X, Liu N, Wang J, Lu T, He L, Tian Y, Fan Z
Molecular cancer 2021 Oct 14;20(1):132
Molecular cancer 2021 Oct 14;20(1):132
ETV4 promotes breast cancer cell stemness by activating glycolysis and CXCR4-mediated sonic Hedgehog signaling.
Zhu T, Zheng J, Zhuo W, Pan P, Li M, Zhang W, Zhou H, Gao Y, Li X, Liu Z
Cell death discovery 2021 May 29;7(1):126
Cell death discovery 2021 May 29;7(1):126
Identification of a potent antagonist of smoothened in hedgehog signaling.
Fan J, Li H, Kuang L, Zhao Z, He W, Liu C, Wang Y, Cheng SY, Chen W
Cell & bioscience 2021 Mar 2;11(1):46
Cell & bioscience 2021 Mar 2;11(1):46
Meningitic Escherichia coli α-hemolysin aggravates blood-brain barrier disruption via targeting TGFβ1-triggered hedgehog signaling.
Fu J, Li L, Huo D, Yang R, Yang B, Xu B, Yang X, Dai M, Tan C, Chen H, Wang X
Molecular brain 2021 Jul 19;14(1):116
Molecular brain 2021 Jul 19;14(1):116
Long noncoding RNA LINC00460 promotes the progression of cervical cancer via regulation of the miR-361-3p/Gli1 axis.
Li F, Zhu W, Wang Z
Human cell 2021 Jan;34(1):229-237
Human cell 2021 Jan;34(1):229-237
Astrocyte-Derived TGFβ1 Facilitates Blood-Brain Barrier Function via Non-Canonical Hedgehog Signaling in Brain Microvascular Endothelial Cells.
Fu J, Li L, Huo D, Zhi S, Yang R, Yang B, Xu B, Zhang T, Dai M, Tan C, Chen H, Wang X
Brain sciences 2021 Jan 8;11(1)
Brain sciences 2021 Jan 8;11(1)
Benzidine promotes the stemness of bladder cancer stem cells via activation of the Sonic hedgehog pathway.
Wang D, Xie D, Bi L, Wang Y, Zou C, Chen L, Geng H, Qian W, Li Y, Sun H, Wang X, Lu Y, Yu D, Zhong C
Oncology letters 2021 Feb;21(2):146
Oncology letters 2021 Feb;21(2):146
Pectin Oligosaccharides Enhance α2,6-Sialylation Modification that Promotes Apoptosis of Bladder Cancer Cells by Targeting the Hedgehog Pathway.
Huang Y, Wang T
Cell biochemistry and biophysics 2021 Dec;79(4):719-728
Cell biochemistry and biophysics 2021 Dec;79(4):719-728
Repair of spinal cord injury in rats via exosomes from bone mesenchymal stem cells requires sonic hedgehog.
Jia Y, Yang J, Lu T, Pu X, Chen Q, Ji L, Luo C
Regenerative therapy 2021 Dec;18:309-315
Regenerative therapy 2021 Dec;18:309-315
Wogonin inhibits the growth of HT144 melanoma via regulating hedgehog signaling-mediated inflammation and glycolysis.
Li L, Ji Y, Zhang L, Cai H, Ji Z, Gu L, Yang S
International immunopharmacology 2021 Dec;101(Pt B):108222
International immunopharmacology 2021 Dec;101(Pt B):108222
Procyanidin B2 alleviates liver injury caused by cold stimulation through Sonic hedgehog signalling and autophagy.
Ma L, Li C, Lian S, Xu B, Lv H, Liu Y, Lu J, Ji H, Li S, Guo J, Yang H
Journal of cellular and molecular medicine 2021 Aug;25(16):8015-8027
Journal of cellular and molecular medicine 2021 Aug;25(16):8015-8027
Rab1A promotes cell proliferation and migration by upregulating Gli1 in colorectal cancer.
Peng C, Li X, Ye Z, Wu W
Scientific reports 2021 Aug 10;11(1):16243
Scientific reports 2021 Aug 10;11(1):16243
Cigarette smoke supports stemness and epithelial-mesenchymal transition in bladder cancer stem cells through SHH signaling.
Sun X, Song J, Li E, Geng H, Li Y, Yu D, Zhong C
International journal of clinical and experimental pathology 2020;13(6):1333-1348
International journal of clinical and experimental pathology 2020;13(6):1333-1348
Liraglutide regulates proliferation, differentiation, and apoptosis of preosteoblasts through a signaling network of Notch/Wnt/Hedgehog signaling pathways.
Hou HW, Xue P, Wang Y, Li YK
European review for medical and pharmacological sciences 2020 Dec;24(23):12408-12422
European review for medical and pharmacological sciences 2020 Dec;24(23):12408-12422
A Combination of BRD4 and HDAC3 Inhibitors Synergistically Suppresses Glioma Stem Cell Growth by Blocking GLI1/IL6/STAT3 Signaling Axis.
Wang Q, Jia S, Wang D, Chen X, Kalvakolanu DV, Zheng H, Wei X, Wen N, Liang H, Guo B, Zhang L
Molecular cancer therapeutics 2020 Dec;19(12):2542-2553
Molecular cancer therapeutics 2020 Dec;19(12):2542-2553
Sonic hedgehog pathway mediates genistein inhibition of renal cancer stem cells.
Li E, Zhang T, Sun X, Li Y, Geng H, Yu D, Zhong C
Oncology letters 2019 Sep;18(3):3081-3091
Oncology letters 2019 Sep;18(3):3081-3091
Genistein inhibits nasopharyngeal cancer stem cells through sonic hedgehog signaling.
Zhang Q, Cao WS, Wang XQ, Zhang M, Lu XM, Chen JQ, Chen Y, Ge MM, Zhong CY, Han HY
Phytotherapy research : PTR 2019 Oct;33(10):2783-2791
Phytotherapy research : PTR 2019 Oct;33(10):2783-2791
TSPAN8 promotes cancer cell stemness via activation of sonic Hedgehog signaling.
Zhu R, Gires O, Zhu L, Liu J, Li J, Yang H, Ju G, Huang J, Ge W, Chen Y, Lu Z, Wang H
Nature communications 2019 Jun 28;10(1):2863
Nature communications 2019 Jun 28;10(1):2863
Sulforaphane inhibits gastric cancer stem cells via suppressing sonic hedgehog pathway.
Ge M, Zhang L, Cao L, Xie C, Li X, Li Y, Meng Y, Chen Y, Wang X, Chen J, Zhang Q, Shao J, Zhong C
International journal of food sciences and nutrition 2019 Aug;70(5):570-578
International journal of food sciences and nutrition 2019 Aug;70(5):570-578
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