RPSA

gene product
37LRP, LAMR1, LRP, p40, SA
Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p40 ribosome-associated protein. The amino acid sequence of laminin receptor 1 is highly conserved through evolution, suggesting a key biological function. It has been observed that the level of the laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype. Multiple copies of this gene exist, however, most of them are pseudogenes thought to have arisen from retropositional events. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
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136 antibodies from 20 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Thermo Fisher Scientific Pierce
3 antibodies
Novus Biologicals
9 antibodies
antibodies-online
47 antibodies
GeneTex
4 antibodies
LifeSpan BioSciences, Inc.
32 antibodies
Proteintech Group
3 antibodies
Aviva Systems Biology
1 antibody
Santa Cruz Biotechnology
1 antibody
Acris Antibodies GmbH
3 antibodies
Abnova Corporation
5 antibodies
RabMAbs
4 antibodies
Creative Biomart
13 antibodies
Enzo Life Sciences
2 antibodies
Abgent
1 antibody
Biorbyt
1 antibody
Bioworld Technology, Inc
1 antibody
EMD Millipore
1 antibody
Sigma-Aldrich
3 antibodies
GenWay
1 antibody
United States Biological
1 antibody