Tissue expression
Cell line expression
Protein structure
PARD6A
Par-6 family cell polarity regulator alphaPAR-6, PAR-6A, PAR6alpha, TAX40, TIP-40
This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Novus Biologicals | ![]() |
1 references | Polyclonal |
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antibodies-online | ![]() |
1 references | Polyclonal |
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LSBio | ![]() |
Polyclonal |
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Invitrogen Antibodies | ![]() |
1 references | Polyclonal |
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Everest Biotech | ![]() |
Polyclonal |
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