Tissue expression
Cell line expression
Protein structure
KLC1
Kinesin light chain 1hKLC1B, hKLC1G, hKLC1J, hKLC1N, hKLC1P, hKLC1R, hKLC1S, KLC, KNS2, KNS2A
Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named ""kinesin 2"", this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos; however, the full-length nature and/or biological validity of most of these variants have not been determined. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Proteintech Group | 19028-1-AP | 1 references | Polyclonal |
WB
EL
ICC
IHC |
|
antibodies-online | ABIN2842389 | 2 references | Polyclonal |
WB
IHC
FC
|
|
Invitrogen Antibodies | MA5-36189 | Monoclonal |
WB
ICC
IHC
FC |
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Biorbyt | orb1726830 | Recombinant |
WB
ICC
IP
IHC
FC
|
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NSJ Bioreagents | RQ6566 | Polyclonal |
WB
EL
ICC
FC |
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Supportive data in Antibodypedia
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Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider