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- References [18]
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- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 19142-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#19142-1-AP, RRID:AB_10638615
- Product name
- GDF8/Myostatin antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated GDF8/Myostatin antibody (Cat. #19142-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Renal Ischemia/Reperfusion Early Induces Myostatin and PCSK9 Expression in Rat Kidneys and HK-2 Cells.
Vitellogenin 2 promotes muscle development and stimulates the browning of white fat.
Inhibition of heat shock protein (HSP) 90 reverses signal transducer and activator of transcription (STAT) 3-mediated muscle wasting in cancer cachexia mice.
Heat stress during late pregnancy of sows influences offspring longissimus dorsi muscle growth at weaning.
The Prophylactic Effects of Glutamine on Muscle Protein Synthesis and Degradation in Rats with Ethanol-Induced Liver Damage.
Differential protein metabolism and regeneration in hypertrophic diaphragm and atrophic gastrocnemius muscles in hibernating Daurian ground squirrels.
Myostatin in the Arterial Wall of Patients with End-Stage Renal Disease.
Skeletal Muscle Anti-Atrophic Effects of Leucine Involve Myostatin Inhibition.
Effect of maternal nutrient restriction on skeletal muscle mass and associated molecular pathways in SGA and Non-SGA sheep fetuses.
Enhanced myostatin expression and signalling promote tubulointerstitial inflammation in diabetic nephropathy.
Mitochondrial dysfunction and inhibition of myoblast differentiation in mice with high-fat-diet-induced pre-diabetes.
Effect of Hypoxia on the Muscle Fiber Switching Signal Pathways CnA/NFATc1 and Myostatin in Mouse Myocytes.
Expression of diaphragmatic myostatin and correlation with apoptosis in rats with chronic obstructive pulmonary disease.
Molecular Cloning, Identification, and Expression Patterns of Myostatin Gene in Water Buffalo (Bubalus Bubalis).
Potential therapeutic interventions for chronic kidney disease-associated sarcopenia via indoxyl sulfate-induced mitochondrial dysfunction.
Indoxyl sulfate potentiates skeletal muscle atrophy by inducing the oxidative stress-mediated expression of myostatin and atrogin-1.
Isozygous and selectable marker-free MSTN knockout cloned pigs generated by the combined use of CRISPR/Cas9 and Cre/LoxP.
Myostatin, follistatin and activin type II receptors are highly expressed in adenomyosis.
Barisione C, Verzola D, Garibaldi S, Ferrari PF, Garibotto G, Ameri P, Pane B, Spinella G, Pratesi G, Palombo D
International journal of molecular sciences 2021 Sep 13;22(18)
International journal of molecular sciences 2021 Sep 13;22(18)
Vitellogenin 2 promotes muscle development and stimulates the browning of white fat.
Li Y, Sun X, Bai Y, Ji Y, Ren H, Yu X, Yan Y, He X, Dong Y, Zhang L, Luo X, Wang H
Aging 2021 Oct 5;13(19):22985-23003
Aging 2021 Oct 5;13(19):22985-23003
Inhibition of heat shock protein (HSP) 90 reverses signal transducer and activator of transcription (STAT) 3-mediated muscle wasting in cancer cachexia mice.
Niu M, Song S, Su Z, Wei L, Li L, Pu W, Zhao C, Ding Y, Wang J, Cao W, Gao Q, Wang H
British journal of pharmacology 2021 Nov;178(22):4485-4500
British journal of pharmacology 2021 Nov;178(22):4485-4500
Heat stress during late pregnancy of sows influences offspring longissimus dorsi muscle growth at weaning.
Li Y, Fan G, Liu Y, Yao W, Albrecht E, Zhao R, Yang X
Research in veterinary science 2021 May;136:336-342
Research in veterinary science 2021 May;136:336-342
The Prophylactic Effects of Glutamine on Muscle Protein Synthesis and Degradation in Rats with Ethanol-Induced Liver Damage.
Xiao Q, Chen YH, Pratama SA, Chen YL, Shirakawa H, Peng HC, Yang SC
Nutrients 2021 Aug 14;13(8)
Nutrients 2021 Aug 14;13(8)
Differential protein metabolism and regeneration in hypertrophic diaphragm and atrophic gastrocnemius muscles in hibernating Daurian ground squirrels.
Yan X, Gao X, Niu Q, Peng X, Zhang J, Ma X, Wei Y, Wang H, Gao Y, Chang H
Experimental physiology 2021 Apr;106(4):958-971
Experimental physiology 2021 Apr;106(4):958-971
Myostatin in the Arterial Wall of Patients with End-Stage Renal Disease.
Esposito P, Verzola D, Porta E, Milanesi S, Grignano MA, Avella A, Gregorini M, Abelli M, Ticozzelli E, Rampino T, Garibotto G
Journal of atherosclerosis and thrombosis 2020 Oct 1;27(10):1039-1052
Journal of atherosclerosis and thrombosis 2020 Oct 1;27(10):1039-1052
Skeletal Muscle Anti-Atrophic Effects of Leucine Involve Myostatin Inhibition.
Cruz A, Ferian A, Alves PKN, Silva WJ, Bento MR, Gasch A, Labeit S, Moriscot AS
DNA and cell biology 2020 Nov 2;
DNA and cell biology 2020 Nov 2;
Effect of maternal nutrient restriction on skeletal muscle mass and associated molecular pathways in SGA and Non-SGA sheep fetuses.
Sandoval C, Lambo CA, Beason K, Dunlap KA, Satterfield MC
Domestic animal endocrinology 2020 Jul;72:106443
Domestic animal endocrinology 2020 Jul;72:106443
Enhanced myostatin expression and signalling promote tubulointerstitial inflammation in diabetic nephropathy.
Verzola D, Milanesi S, Viazzi F, Ansaldo F, Saio M, Garibaldi S, Carta A, Costigliolo F, Salvidio G, Barisione C, Esposito P, Garibotto G, Picciotto D
Scientific reports 2020 Apr 14;10(1):6343
Scientific reports 2020 Apr 14;10(1):6343
Mitochondrial dysfunction and inhibition of myoblast differentiation in mice with high-fat-diet-induced pre-diabetes.
Xu D, Jiang Z, Sun Z, Wang L, Zhao G, Hassan HM, Fan S, Zhou W, Han S, Zhang L, Wang T
Journal of cellular physiology 2019 May;234(5):7510-7523
Journal of cellular physiology 2019 May;234(5):7510-7523
Effect of Hypoxia on the Muscle Fiber Switching Signal Pathways CnA/NFATc1 and Myostatin in Mouse Myocytes.
Lixin L, Juan W, Yun B, Jingwei L, Xiuju Y, Xiaomao L, Zhiwei Z, Xiaoyan H, Yanjun D, Hongquan L, Haidong W
Acta histochemica 2019 Jul;121(5):539-545
Acta histochemica 2019 Jul;121(5):539-545
Expression of diaphragmatic myostatin and correlation with apoptosis in rats with chronic obstructive pulmonary disease.
Zhou X, Yi D, Wu Y, Pei X, Yu H, Chen Y, Jiang Y, Li W
Experimental and therapeutic medicine 2018 Mar;15(3):2295-2300
Experimental and therapeutic medicine 2018 Mar;15(3):2295-2300
Molecular Cloning, Identification, and Expression Patterns of Myostatin Gene in Water Buffalo (Bubalus Bubalis).
Zhu P, Li H, Huang G, Cui J, Zhang R, Cui K, Yang S, Shi D
Animal biotechnology 2018 Jan 2;29(1):26-33
Animal biotechnology 2018 Jan 2;29(1):26-33
Potential therapeutic interventions for chronic kidney disease-associated sarcopenia via indoxyl sulfate-induced mitochondrial dysfunction.
Enoki Y, Watanabe H, Arake R, Fujimura R, Ishiodori K, Imafuku T, Nishida K, Sugimoto R, Nagao S, Miyamura S, Ishima Y, Tanaka M, Matsushita K, Komaba H, Fukagawa M, Otagiri M, Maruyama T
Journal of cachexia, sarcopenia and muscle 2017 Oct;8(5):735-747
Journal of cachexia, sarcopenia and muscle 2017 Oct;8(5):735-747
Indoxyl sulfate potentiates skeletal muscle atrophy by inducing the oxidative stress-mediated expression of myostatin and atrogin-1.
Enoki Y, Watanabe H, Arake R, Sugimoto R, Imafuku T, Tominaga Y, Ishima Y, Kotani S, Nakajima M, Tanaka M, Matsushita K, Fukagawa M, Otagiri M, Maruyama T
Scientific reports 2016 Aug 23;6:32084
Scientific reports 2016 Aug 23;6:32084
Isozygous and selectable marker-free MSTN knockout cloned pigs generated by the combined use of CRISPR/Cas9 and Cre/LoxP.
Bi Y, Hua Z, Liu X, Hua W, Ren H, Xiao H, Zhang L, Li L, Wang Z, Laible G, Wang Y, Dong F, Zheng X
Scientific reports 2016 Aug 17;6:31729
Scientific reports 2016 Aug 17;6:31729
Myostatin, follistatin and activin type II receptors are highly expressed in adenomyosis.
Carrarelli P, Yen CF, Arcuri F, Funghi L, Tosti C, Wang TH, Huang JS, Petraglia F
Fertility and sterility 2015 Sep;104(3):744-52.e1
Fertility and sterility 2015 Sep;104(3):744-52.e1
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse heart tissue were subjected to SDS PAGE followed by western blot with 19142-1-AP( MSTN Antibody) at dilution of 1:600
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human heart using 19142-1-AP(MSTN antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The GDF8/Myostatin antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human GDF8/Myostatin. This antibody recognizes human,mouse,rat antigen. The GDF8/Myostatin antibody has been validated for the following applications: ELISA, IHC, WB analysis.
