PGK1

gene product
The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. Additionally, this protein is secreted by tumor cells where it participates in angiogenesis by functioning to reduce disulfide bonds in the serine protease, plasmin, which consequently leads to the release of the tumor blood vessel inhibitor angiostatin. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Deficiency of the enzyme is associated with a wide range of clinical phenotypes hemolytic anemia and neurological impairment. Pseudogenes of this gene have been defined on chromosomes 19, 21 and the X chromosome. [provided by RefSeq, Jan 2014]
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186 antibodies from 22 providers.

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AntibodyRefsTypeKDWBELICCIPIHCFC
Abgent
3 antibodies
Abnova Corporation
5 antibodies
GeneTex
2 antibodies
Thermo Fisher Scientific Pierce
4 antibodies
Aviva Systems Biology
4 antibodies
Novus Biologicals
6 antibodies
Santa Cruz Biotechnology
1 antibody
antibodies-online
76 antibodies
Bioworld Technology, Inc
1 antibody
Proteintech Group
1 antibody
Acris Antibodies GmbH
7 antibodies
Biorbyt
15 antibodies
OriGene
2 antibodies
LifeSpan BioSciences, Inc.
23 antibodies
United States Biological
9 antibodies
BosterBio
1 antibody
R&D Systems
1 antibody
RabMAbs
2 antibodies
Creative Diagnostics
5 antibodies
Sigma-Aldrich
5 antibodies
RayBiotech, Inc.
1 antibody