ABIN152978

antibody from antibodies-online

Targeting: TRIM28 KAP1, PPP1R157, RNF96, TF1B, TIF1B

Provider product page for ABIN152978

Western blot

Immunocytochemistry

Immunoprecipitation

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [14]
Comments [0]
Validations
Western blot [4]
Immunocytochemistry [1]
Immunohistochemistry [3]

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Product number: ABIN152978 - Provider product page
Provider: antibodies-online
Product name: anti-Tripartite Motif Containing 28 (TRIM28) (AA 1-50) antibody
Antibody type: Polyclonal
Description: Immunogen affinity purified
Reactivity: Human, Mouse
Host: Rabbit
Epitope: AA 1-50
Vial size: 100 μL
Storage: Store at 4°C. Do not freeze.
Handling: Do not freeze.

TRIM28 protein structure - ABIN152978 shown in red.

Submitted references Cockayne syndrome group B protein regulates DNA double-strand break repair and checkpoint activation.

Batenburg NL, Thompson EL, Hendrickson EA, Zhu XD
The EMBO journal 2015 May 12;34(10):1399-416

MAGE-C2 promotes growth and tumorigenicity of melanoma cells, phosphorylation of KAP1, and DNA damage repair.

Bhatia N, Xiao TZ, Rosenthal KA, Siddiqui IA, Thiyagarajan S, Smart B, Meng Q, Zuleger CL, Mukhtar H, Kenney SC, Albertini MR, Jack Longley B
The Journal of investigative dermatology 2013 Mar;133(3):759-767

Loss of caspase-2 augments lymphomagenesis and enhances genomic instability in Atm-deficient mice.

Puccini J, Shalini S, Voss AK, Gatei M, Wilson CH, Hiwase DK, Lavin MF, Dorstyn L, Kumar S
Proceedings of the National Academy of Sciences of the United States of America 2013 Dec 3;110(49):19920-5

Acetylated hsp70 and KAP1-mediated Vps34 SUMOylation is required for autophagosome creation in autophagy.

Yang Y, Fiskus W, Yong B, Atadja P, Takahashi Y, Pandita TK, Wang HG, Bhalla KN
Proceedings of the National Academy of Sciences of the United States of America 2013 Apr 23;110(17):6841-6

ATM protein-dependent phosphorylation of Rad50 protein regulates DNA repair and cell cycle control.

Gatei M, Jakob B, Chen P, Kijas AW, Becherel OJ, Gueven N, Birrell G, Lee JH, Paull TT, Lerenthal Y, Fazry S, Taucher-Scholz G, Kalb R, Schindler D, Waltes R, Dörk T, Lavin MF
The Journal of biological chemistry 2011 Sep 9;286(36):31542-56

A multiprotein binding interface in an intrinsically disordered region of the tumor suppressor protein interferon regulatory factor-1.

Narayan V, Halada P, Hernychová L, Chong YP, Žáková J, Hupp TR, Vojtesek B, Ball KL
The Journal of biological chemistry 2011 Apr 22;286(16):14291-303

Identification of novel small molecules that inhibit protein-protein interactions between MAGE and KAP-1.

Bhatia N, Yang B, Xiao TZ, Peters N, Hoffmann MF, Longley BJ
Archives of biochemistry and biophysics 2011 Apr 15;508(2):217-21

Interactions of ErbB4 and Kap1 connect the growth factor and DNA damage response pathways.

Gilmore-Hebert M, Ramabhadran R, Stern DF
Molecular cancer research : MCR 2010 Oct;8(10):1388-98

KRAB zinc-finger proteins localise to novel KAP1-containing foci that are adjacent to PML nuclear bodies.

Briers S, Crawford C, Bickmore WA, Sutherland HG
Journal of cell science 2009 Apr 1;122(Pt 7):937-46

Physical and functional interactions between STAT3 and KAP1.

Tsuruma R, Ohbayashi N, Kamitani S, Ikeda O, Sato N, Muromoto R, Sekine Y, Oritani K, Matsuda T
Oncogene 2008 May 8;27(21):3054-9

MAGE-A, mMage-b, and MAGE-C proteins form complexes with KAP1 and suppress p53-dependent apoptosis in MAGE-positive cell lines.

Yang B, O'Herrin SM, Wu J, Reagan-Shaw S, Ma Y, Bhat KM, Gravekamp C, Setaluri V, Peters N, Hoffmann FM, Peng H, Ivanov AV, Simpson AJ, Longley BJ
Cancer research 2007 Oct 15;67(20):9954-62

Regulation of E2F1 function by the nuclear corepressor KAP1.

Wang C, Rauscher FJ 3rd, Cress WD, Chen J
The Journal of biological chemistry 2007 Oct 12;282(41):29902-9

Chromatin relaxation in response to DNA double-strand breaks is modulated by a novel ATM- and KAP-1 dependent pathway.

Ziv Y, Bielopolski D, Galanty Y, Lukas C, Taya Y, Schultz DC, Lukas J, Bekker-Jensen S, Bartek J, Shiloh Y
Nature cell biology 2006 Aug;8(8):870-6

MDM2 interaction with nuclear corepressor KAP1 contributes to p53 inactivation.

Wang C, Ivanov A, Chen L, Fredericks WJ, Seto E, Rauscher FJ 3rd, Chen J
The EMBO journal 2005 Sep 21;24(18):3279-90

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