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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- PAB4718 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB4718, RRID:AB_1579950
- Product name
- S1PR1 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of S1PR1.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Transduction of multiple effects of sphingosine 1-phosphate (S1P) on T cell functions by the S1P1 G protein-coupled receptor.
Inhibition of Ca(2+) signalling by the sphingosine 1-phosphate receptor S1P(1).
Dual regulation of EDG1/S1P(1) receptor phosphorylation and internalization by protein kinase C and G-protein-coupled receptor kinase 2.
Dorsam G, Graeler MH, Seroogy C, Kong Y, Voice JK, Goetzl EJ
Journal of immunology (Baltimore, Md. : 1950) 2003 Oct 1;171(7):3500-7
Journal of immunology (Baltimore, Md. : 1950) 2003 Oct 1;171(7):3500-7
Inhibition of Ca(2+) signalling by the sphingosine 1-phosphate receptor S1P(1).
zu Heringdorf DM, Vincent ME, Lipinski M, Danneberg K, Stropp U, Wang DA, Tigyi G, Jakobs KH
Cellular signalling 2003 Jul;15(7):677-87
Cellular signalling 2003 Jul;15(7):677-87
Dual regulation of EDG1/S1P(1) receptor phosphorylation and internalization by protein kinase C and G-protein-coupled receptor kinase 2.
Watterson KR, Johnston E, Chalmers C, Pronin A, Cook SJ, Benovic JL, Palmer TM
The Journal of biological chemistry 2002 Feb 22;277(8):5767-77
The Journal of biological chemistry 2002 Feb 22;277(8):5767-77
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of mouse lung tissue lysate (35 ug/lane) with S1PR1 polyclonal antibody (Cat # PAB4718).
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with S1PR1 polyclonal antibody (Cat # PAB4718) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
