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- Antibody Data
- Antigen structure
- References [4]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- ABIN500650 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Sphingosine-1-Phosphate Receptor 1 (S1PR1) (C-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- S1P1 antibody was raised against a 14 amino acid peptide near the carboxy terminus of the Human S1P1.
- Description
- Peptide Affinity Chromatography
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- C-Term
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 1.0 mg/mL
- Storage
- Store the antibody undiluted at 2-8°C.
Submitted references The sphingosine 1-phosphate receptor 1 causes tissue retention by inhibiting the entry of peripheral tissue T lymphocytes into afferent lymphatics.
S1P1 receptor signaling overrides retention mediated by G alpha i-coupled receptors to promote T cell egress.
Lymphocyte trafficking across high endothelial venules: dogmas and enigmas.
Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists.
Ledgerwood LG, Lal G, Zhang N, Garin A, Esses SJ, Ginhoux F, Merad M, Peche H, Lira SA, Ding Y, Yang Y, He X, Schuchman EH, Allende ML, Ochando JC, Bromberg JS
Nature immunology 2008 Jan;9(1):42-53
Nature immunology 2008 Jan;9(1):42-53
S1P1 receptor signaling overrides retention mediated by G alpha i-coupled receptors to promote T cell egress.
Pham TH, Okada T, Matloubian M, Lo CG, Cyster JG
Immunity 2008 Jan;28(1):122-33
Immunity 2008 Jan;28(1):122-33
Lymphocyte trafficking across high endothelial venules: dogmas and enigmas.
Miyasaka M, Tanaka T
Nature reviews. Immunology 2004 May;4(5):360-70
Nature reviews. Immunology 2004 May;4(5):360-70
Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists.
Mandala S, Hajdu R, Bergstrom J, Quackenbush E, Xie J, Milligan J, Thornton R, Shei GJ, Card D, Keohane C, Rosenbach M, Hale J, Lynch CL, Rupprecht K, Parsons W, Rosen H
Science (New York, N.Y.) 2002 Apr 12;296(5566):346-9
Science (New York, N.Y.) 2002 Apr 12;296(5566):346-9
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of S1P1 in Mouse thymus lysate with EDG-1 / S1PR1 Antibody Cat.-No AP30748PU-N at 1 μg/ml (A) and 2 ?g/ml (B).
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunohistochemistry of S1P1 in Mouse thymus tissue with EDG-1 / S1PR1 Antibody Cat.-No AP30748PU-N at 5 ?g/ml.
