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Western blot
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Western blot [1]
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- Product number
- BS3486 - Provider product page
- Provider
- Bioworld Technology, Inc
- Proper citation
- Bioworld Technology Cat#BS3486, RRID:AB_1662717
- Product name
- IFN ÎÛ (Q69) polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide, corresponding to amino acids 31-80 of Human IFN-ÎÛ.
- Description
- Interferon (IFN)-ÎÛ is an antiviral and antiparasitic agent produced by CD4+/CD8+ lymphocytes and natural killer cells that undergo activation by antigens, mitogens or alloantigens. IFN-ÎÛ production modulates T cell growth and differentiation and inhibits the growth of B cells. Synthesis of IFN-ÎÛ is inducible by IL-2, FGF and EGF. The active form of IFN-ÎÛ is a homodimer with each subunit containing six helices. The dimeric structure of human IFN-ÎÛ is stabilized by non-covalent interactions through the interface of the helices. IFN-ÎÛ tranlsated precursor is 166 amino acids, including the 23 amino acid secretory sequence. Multiple forms exist due to variable glycosylation and under non-denaturing conditions due to dimers and tetramers.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
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- Experimental details
- Western blot (WB) analysis of IFN-¦Ã (Q69) pAb at 1:500 dilutionLane1:HEK293T whole cell lysateLane2:Raw264.7 whole cell lysateLane3:H9C2 whole cell lysate
