ABIN252586

antibody from antibodies-online

Targeting: SOCS1 Cish1, JAB, SOCS-1, SSI-1, TIP3

Western blot (Supportive data in Antibodypedia)

Antibody Data

Product number

ABIN252586

Provider

antibodies-online

Product name

anti-Suppressor of Cytokine Signaling 1 (SOCS1) antibody

Antibody type

Polyclonal

Description

Unpurified

Reactivity

Human, Mouse

Host

Rabbit

Vial size

0.2 mL

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Handling

Avoid freeze-thaw cycles

References

Submitted references

SOCS-1 mediates ubiquitylation and degradation of GM-CSF receptor.

Bunda S, Kommaraju K, Heir P, Ohh M
PloS one 2013;8(9):e76370

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Loss of JAK2 regulation via a heterodimeric VHL-SOCS1 E3 ubiquitin ligase underlies Chuvash polycythemia.

Russell RC, Sufan RI, Zhou B, Heir P, Bunda S, Sybingco SS, Greer SN, Roche O, Heathcote SA, Chow VW, Boba LM, Richmond TD, Hickey MM, Barber DL, Cheresh DA, Simon MC, Irwin MS, Kim WY, Ohh M
Nature medicine 2011 Jun 19;17(7):845-53

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IL-7 engages multiple mechanisms to overcome chronic viral infection and limit organ pathology.

Pellegrini M, Calzascia T, Toe JG, Preston SP, Lin AE, Elford AR, Shahinian A, Lang PA, Lang KS, Morre M, Assouline B, Lahl K, Sparwasser T, Tedder TF, Paik JH, DePinho RA, Basta S, Ohashi PS, Mak TW
Cell 2011 Feb 18;144(4):601-13

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SOCS1 regulates the IFN but not NFkappaB pathway in TLR-stimulated human monocytes and macrophages.

Prêle CM, Woodward EA, Bisley J, Keith-Magee A, Nicholson SE, Hart PH
Journal of immunology (Baltimore, Md. : 1950) 2008 Dec 1;181(11):8018-26

Western blot

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

WB