Tissue expression
Cell line expression
Protein structure
TFAP2B
Transcription factor AP-2 betaAP2-B
This gene encodes a member of the AP-2 family of transcription factors. AP-2 proteins form homo- or hetero-dimers with other AP-2 family members and bind specific DNA sequences. They are thought to stimulate cell proliferation and suppress terminal differentiation of specific cell types during embryonic development. Specific AP-2 family members differ in their expression patterns and binding affinity for different promoters. This protein functions as both a transcriptional activator and repressor. Mutations in this gene result in autosomal dominant Char syndrome, suggesting that this gene functions in the differentiation of neural crest cell derivatives. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Proteintech Group | 13183-1-AP | 1 references | Polyclonal |
WB
EL
IP
|
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antibodies-online | ABIN394169 | 5 references | Monoclonal |
WB
ICC |
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Santa Cruz Biotechnology | sc-8976 | 2 references | Polyclonal |
WB
IHC |
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LSBio | LS-C198327 | Monoclonal |
WB
EL
ICC
|
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Invitrogen Antibodies | MA5-31927 | Monoclonal |
WB
EL
FC
|
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