Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 15271-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15271-1-AP, RRID:AB_2127260
- Product name
- INTS10 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated INTS10 antibody (Cat. #15271-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Integrator Recruits Protein Phosphatase 2A to Prevent Pause Release and Facilitate Transcription Termination.
INTS10-INTS13-INTS14 form a functional module of Integrator that binds nucleic acids and the cleavage module.
Molecular basis for the interaction between Integrator subunits IntS9 and IntS11 and its functional importance.
CRISPR-Cas9 mediated genetic engineering for the purification of the endogenous integrator complex from mammalian cells.
DSIF and NELF interact with Integrator to specify the correct post-transcriptional fate of snRNA genes.
Huang KL, Jee D, Stein CB, Elrod ND, Henriques T, Mascibroda LG, Baillat D, Russell WK, Adelman K, Wagner EJ
Molecular cell 2020 Oct 15;80(2):345-358.e9
Molecular cell 2020 Oct 15;80(2):345-358.e9
INTS10-INTS13-INTS14 form a functional module of Integrator that binds nucleic acids and the cleavage module.
Sabath K, Stäubli ML, Marti S, Leitner A, Moes M, Jonas S
Nature communications 2020 Jul 9;11(1):3422
Nature communications 2020 Jul 9;11(1):3422
Molecular basis for the interaction between Integrator subunits IntS9 and IntS11 and its functional importance.
Wu Y, Albrecht TR, Baillat D, Wagner EJ, Tong L
Proceedings of the National Academy of Sciences of the United States of America 2017 Apr 25;114(17):4394-4399
Proceedings of the National Academy of Sciences of the United States of America 2017 Apr 25;114(17):4394-4399
CRISPR-Cas9 mediated genetic engineering for the purification of the endogenous integrator complex from mammalian cells.
Baillat D, Russell WK, Wagner EJ
Protein expression and purification 2016 Dec;128:101-8
Protein expression and purification 2016 Dec;128:101-8
DSIF and NELF interact with Integrator to specify the correct post-transcriptional fate of snRNA genes.
Yamamoto J, Hagiwara Y, Chiba K, Isobe T, Narita T, Handa H, Yamaguchi Y
Nature communications 2014 Jun 27;5:4263
Nature communications 2014 Jun 27;5:4263
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The INTS10 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human INTS10. This antibody recognizes human, mouse, rat antigen. The INTS10 antibody has been validated for the following applications: ELISA, WB analysis.