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Learnsc-28269
antibody from Santa Cruz Biotechnology
Targeting: TNNT1
ANM, FLJ98147, MGC104241, NEM5, STNT, TNT, TNTS
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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- Product number
- sc-28269 - Provider product page
- Provider
- Santa Cruz Biotechnology
- Proper citation
- Santa Cruz Biotechnology Cat#sc-28269, RRID:AB_2206426
- Product name
- Anti-TNNT1
- Antibody type
- Polyclonal
- Antigen
- Recombinant full-length protein
- Reactivity
- Human
- Host
- Rabbit
Submitted references Altered myofilament function depresses force generation in patients with nebulin-based nemaline myopathy (NEM2).
Nebulin alters cross-bridge cycling kinetics and increases thin filament activation: a novel mechanism for increasing tension and reducing tension cost.
Ottenheijm CA, Hooijman P, DeChene ET, Stienen GJ, Beggs AH, Granzier H
Journal of structural biology 2010 May;170(2):334-43
Journal of structural biology 2010 May;170(2):334-43
Nebulin alters cross-bridge cycling kinetics and increases thin filament activation: a novel mechanism for increasing tension and reducing tension cost.
Chandra M, Mamidi R, Ford S, Hidalgo C, Witt C, Ottenheijm C, Labeit S, Granzier H
The Journal of biological chemistry 2009 Nov 6;284(45):30889-96
The Journal of biological chemistry 2009 Nov 6;284(45):30889-96
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Supportive validation
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- Main image
- Experimental details
- Immunohistochemical staining of human skeletal muscle shows distinct cytoplasmic positivity in myocytes.
- Validation comment
- Staining pattern partly consistent with experimental and/or bioinformatic data.
