AMM02470G

antibody from Leading Biology

Targeting: VRK1

Western blot (Recommended by provider)

Antibody Data

Product number

AMM02470G

Provider

Leading Biology

Product name

VRK1 Antibody (Center)(Ascites)

Antibody type

Monoclonal

Description

Serine/threonine kinase involved in Golgi disassembly during the cell cycle: following phosphorylation by PLK3 during mitosis, required to induce Golgi fragmentation. Acts by mediating phosphorylation of downstream target protein. Phosphorylates 'Thr-18' of p53/TP53 and may thereby prevent the interaction between p53/TP53 and MDM2. Phosphorylates casein and histone H3. Phosphorylates BANF1: disrupts its ability to bind DNA, reduces its binding to LEM domain-containing proteins and causes its relocalization from the nucleus to the cytoplasm.

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

1015CT2.1.1

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.