Tissue expression
Cell line expression
Protein structure
PZP
PZP alpha-2-macroglobulin likeCPAMD6
The protein encoded by this gene is highly expressed in late-pregnancy serum and is similar in structure to alpha-2-macroglobulin. The encoded protein, which acts as a homotetramer, inhibits the activity of all four classes of proteinases. This protein contains cleavage sites for several proteinases. Upon binding of a proteinase, the conformation of this protein changes to trap the proteinase, limiting its activity. This protein appears to be elevated in the sera of presymptomatic Alzheimer's disease patients. [provided by RefSeq, Dec 2016]
Top validated antibodies |
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Proteintech Group | 21742-1-AP | 1 references | Polyclonal |
WB
EL
IHC
|
|
Biorbyt | orb2207213 | Polyclonal |
WB
ICC
IP
IHC |
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Invitrogen Antibodies | PA5-110249 | 1 references | Polyclonal |
WB
OA |
|
NovoPro Bioscience Inc. | 114181 | Polyclonal |
WB
EL
IHC
|
||
FineTest Biotech | FNab06763 | Polyclonal |
WB
EL
IHC
|
All Antibodies
Filters
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider