ABIN950532

antibody from antibodies-online

Targeting: ASCL2 ASH2, bHLHa45, HASH2

Provider product page for ABIN950532

Western blot

Antibody data

Antibody Data
Antigen structure
References [5]
Comments [0]
Validations
Western blot [1]

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Product number: ABIN950532 - Provider product page
Provider: antibodies-online
Product name: anti-Achaete-Scute Complex Homolog 2 (Drosophila) (ASCL2) (AA 38-65), (N-Term) antibody
Antibody type: Polyclonal
Description: Affinity chromatography on Protein A
Reactivity: Human, Mouse
Host: Rabbit
Epitope: N-Term, AA 38-65
Vial size: 0.4 mL
Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Handling: Avoid repeated freezing and thawing.

ASCL2 protein structure - ABIN950532 shown in red.

Submitted references Expression of an ASCL2 related stem cell signature and IGF2 in colorectal cancer liver metastases with 11p15.5 gain.

Stange DE, Engel F, Longerich T, Koo BK, Koch M, Delhomme N, Aigner M, Toedt G, Schirmacher P, Lichter P, Weitz J, Radlwimmer B
Gut 2010 Sep;59(9):1236-44

Identification of seven new prostate cancer susceptibility loci through a genome-wide association study.

Eeles RA, Kote-Jarai Z, Al Olama AA, Giles GG, Guy M, Severi G, Muir K, Hopper JL, Henderson BE, Haiman CA, Schleutker J, Hamdy FC, Neal DE, Donovan JL, Stanford JL, Ostrander EA, Ingles SA, John EM, Thibodeau SN, Schaid D, Park JY, Spurdle A, Clements J, Dickinson JL, Maier C, Vogel W, Dörk T, Rebbeck TR, Cooney KA, Cannon-Albright L, Chappuis PO, Hutter P, Zeegers M, Kaneva R, Zhang HW, Lu YJ, Foulkes WD, English DR, Leongamornlert DA, Tymrakiewicz M, Morrison J, Ardern-Jones AT, Hall AL, O'Brien LT, Wilkinson RA, Saunders EJ, Page EC, Sawyer EJ, Edwards SM, Dearnaley DP, Horwich A, Huddart RA, Khoo VS, Parker CC, Van As N, Woodhouse CJ, Thompson A, Christmas T, Ogden C, Cooper CS, Southey MC, Lophatananon A, Liu JF, Kolonel LN, Le Marchand L, Wahlfors T, Tammela TL, Auvinen A, Lewis SJ, Cox A, FitzGerald LM, Koopmeiners JS, Karyadi DM, Kwon EM, Stern MC, Corral R, Joshi AD, Shahabi A, McDonnell SK, Sellers TA, Pow-Sang J, Chambers S, Aitken J, Gardiner RA, Batra J, Kedda MA, Lose F, Polanowski A, Patterson B, Serth J, Meyer A, Luedeke M, Stefflova K, Ray AM, Lange EM, Farnham J, Khan H, Slavov C, Mitkova A, Cao G, UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology., UK ProtecT Study Collaborators., PRACTICAL Consortium., Easton DF
Nature genetics 2009 Oct;41(10):1116-21

Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.

Barrett JC, Clayton DG, Concannon P, Akolkar B, Cooper JD, Erlich HA, Julier C, Morahan G, Nerup J, Nierras C, Plagnol V, Pociot F, Schuilenburg H, Smyth DJ, Stevens H, Todd JA, Walker NM, Rich SS, Type 1 Diabetes Genetics Consortium.
Nature genetics 2009 Jun;41(6):703-7

Detection of HASH2 (ASCL2) gene expression in gestational trophoblastic disease.

Shahib MN, Martaadisoebrata D, Kato H
The Journal of reproductive medicine 2006 Nov;51(11):892-6

Achaete-scute like 2 (ascl2) is a target of Wnt signalling and is upregulated in intestinal neoplasia.

Jubb AM, Chalasani S, Frantz GD, Smits R, Grabsch HI, Kavi V, Maughan NJ, Hillan KJ, Quirke P, Koeppen H
Oncogene 2006 Jun 8;25(24):3445-57