Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
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- Product number
- 15523-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15523-1-AP, RRID:AB_2132006
- Product name
- KCTD12 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated KCTD12 antibody (Cat. #15523-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The effects of Kctd12, an auxiliary subunit of GABAB receptor in dentate gyrus on behavioral response to chronic social defeat stress in mice.
The Electrophysiological Determinants of Corticospinal Motor Neuron Vulnerability in ALS.
Mice lacking the transcriptional regulator Bhlhe40 have enhanced neuronal excitability and impaired synaptic plasticity in the hippocampus.
KCTD12 promotes tumorigenesis by facilitating CDC25B/CDK1/Aurora A-dependent G2/M transition.
Lentiviral-mediated overexpression of KCTD12 inhibits the proliferation of human uveal melanoma OCM-1 cells.
KCTD12 Regulates Colorectal Cancer Cell Stemness through the ERK Pathway.
Deng SL, Hu ZL, Mao L, Gao B, Yang Q, Wang F, Chen JG
Pharmacological research 2021 Jan;163:105355
Pharmacological research 2021 Jan;163:105355
The Electrophysiological Determinants of Corticospinal Motor Neuron Vulnerability in ALS.
Jara JH, Sheets PL, Nigro MJ, Perić M, Brooks C, Heller DB, Martina M, Andjus PR, Ozdinler PH
Frontiers in molecular neuroscience 2020;13:73
Frontiers in molecular neuroscience 2020;13:73
Mice lacking the transcriptional regulator Bhlhe40 have enhanced neuronal excitability and impaired synaptic plasticity in the hippocampus.
Hamilton KA, Wang Y, Raefsky SM, Berkowitz S, Spangler R, Suire CN, Camandola S, Lipsky RH, Mattson MP
PloS one 2018;13(5):e0196223
PloS one 2018;13(5):e0196223
KCTD12 promotes tumorigenesis by facilitating CDC25B/CDK1/Aurora A-dependent G2/M transition.
Zhong Y, Yang J, Xu WW, Wang Y, Zheng CC, Li B, He QY
Oncogene 2017 Nov 2;36(44):6177-6189
Oncogene 2017 Nov 2;36(44):6177-6189
Lentiviral-mediated overexpression of KCTD12 inhibits the proliferation of human uveal melanoma OCM-1 cells.
Luo L, Cui J, Feng Z, Li Y, Wang M, Cai Y, Wu Y, Jin J
Oncology reports 2017 Feb;37(2):871-878
Oncology reports 2017 Feb;37(2):871-878
KCTD12 Regulates Colorectal Cancer Cell Stemness through the ERK Pathway.
Li L, Duan T, Wang X, Zhang RH, Zhang M, Wang S, Wang F, Wu Y, Huang H, Kang T
Scientific reports 2016 Feb 5;6:20460
Scientific reports 2016 Feb 5;6:20460
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 15523-1-AP(KCTD12 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using KCTD12 antibody 15523-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line