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Western blot
Immunocytochemistry
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [4]
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- Validations
- Immunocytochemistry [1]
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- Product number
- ALX-805-704-C100 - Provider product page
- Provider
- Enzo Life Sciences
- Proper citation
- Enzo Life Sciences Cat#ALX-805-704-C100, RRID:AB_2051621
- Product name
- HLA-G (human) monoclonal antibody (MEM-G/1)
- Antibody type
- Monoclonal
- Antigen
- Recombinant full length protein
- Description
- Protein A affinity chromatography.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- MEM-G/1
- Vial size
- 100 μg
- Storage
- -20°C
- Handling
- Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20¡C.
Submitted references A critical look at HLA-G.
Disulfide bond-mediated dimerization of HLA-G on the cell surface.
Comparative reactivity of different HLA-G monoclonal antibodies to soluble HLA-G molecules.
Melanomas and melanoma cell lines do not express HLA-G, and the expression cannot be induced by gammaIFN treatment.
Apps R, Gardner L, Moffett A
Trends in immunology 2008 Jul;29(7):313-21
Trends in immunology 2008 Jul;29(7):313-21
Disulfide bond-mediated dimerization of HLA-G on the cell surface.
Boyson JE, Erskine R, Whitman MC, Chiu M, Lau JM, Koopman LA, Valter MM, Angelisova P, Horejsi V, Strominger JL
Proceedings of the National Academy of Sciences of the United States of America 2002 Dec 10;99(25):16180-5
Proceedings of the National Academy of Sciences of the United States of America 2002 Dec 10;99(25):16180-5
Comparative reactivity of different HLA-G monoclonal antibodies to soluble HLA-G molecules.
Fournel S, Huc X, Aguerre-Girr M, Solier C, Legros M, Praud-Brethenou C, Moussa M, Chaouat G, Berrebi A, Bensussan A, Lenfant F, Le Bouteiller P
Tissue antigens 2000 Jun;55(6):510-8
Tissue antigens 2000 Jun;55(6):510-8
Melanomas and melanoma cell lines do not express HLA-G, and the expression cannot be induced by gammaIFN treatment.
Frumento G, Franchello S, Palmisano GL, Nicotra MR, Giacomini P, Loke YW, Geraghty DE, Maio M, Manzo C, Natali PG, Ferrara GB
Tissue antigens 2000 Jul;56(1):30-7
Tissue antigens 2000 Jul;56(1):30-7
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Supportive validation
- Submitted by
- Enzo Life Sciences (provider)
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- Experimental details
- Immunohistochemistry analysis (AEC visualization) of paraffin embedded section of human lung carcinoma using Prod. No. ALX-805-704. The antibody MEM-G/1 detects HLA-G molecules in activated macrophages infiltrating lung carcinomas. . The expression of HLA-G in myelo-monocytic cells infiltrating lung pathologic tissues could alter antigenic presentation and contribute to decrease immune response efficiency, subsequently favoring the progression of tumoral or inflammatory process.
