NXF1

gene product
DKFZp667O0311, Mex67, TAP
This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. It is the vertebrate homologue of the yeast protein Mex67p. The encoded protein overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
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84 antibodies from 18 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
GeneTex
4 antibodies
Novus Biologicals
3 antibodies
Thermo Fisher Scientific Pierce
4 antibodies
Proteintech Group
1 antibody
antibodies-online
20 antibodies
Signalway Antibody LLC
2 antibodies
LifeSpan BioSciences, Inc.
9 antibodies
Aviva Systems Biology
7 antibodies
Abnova Corporation
1 antibody
Santa Cruz Biotechnology
1 antibody
Bethyl Laboratories, Inc.
3 antibodies
RabMAbs
5 antibodies
Creative Biomart
8 antibodies
Sigma-Aldrich
3 antibodies
EMD Millipore
2 antibodies
United States Biological
7 antibodies
GenWay
3 antibodies
Cell Signaling Technology, Inc
1 antibody