CST9L

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a protein similar to mouse cystatin 9. Based on its testis-specific expression, it is likely to have a role in tissue reorganization during early testis development. [provided by RefSeq, Jul 2008]

Description

Cystatin 9 like

Tissue specificity

Group enriched (epididymis, testis)

Predicted location

Secreted in male reproductive system

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted secreted proteins
Protein evidence (Kim et al 2014)

Chromosome

20 (23564732 - 23568484)

Ensembl ID

ENSG00000101435  (ver. 103.38)

Orthologs

-

UniProt

Q9H4G1

neXtProt

NX_Q9H4G1

Human splice variants

Protein structure