Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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- Product number
- MA5-11273 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- Anti-E2F4 Monoclonal Antibody (4E2F04 (WUF10)), Biotin
- Antibody type
- Monoclonal
- Antigen
- Recombinant full-length protein
- Description
- MA5-11276 targets E2F-4 Transcription Factor in GS, IF, IHC (P), and WB applications and shows reactivity with Human and Rat samples. The MA5-11276 immunogen is recombinant human E2F-4 protein.
- Reactivity
- Human, Rat
- Host
- Mouse
- Conjugate
- Biotin
- Isotype
- IgG
- Antibody clone number
- 4E2F04 (WUF10)
- Vial size
- 500 µL
- Concentration
- 0.2 mg/ml
- Storage
- 4° C
Submitted references Anti-apoptotic function of the E2F transcription factor 4 (E2F4)/p130, a member of retinoblastoma gene family in cardiac myocytes.
Effects of isotretinoin on spermatogenesis of rats.
Classical Hodgkin lymphoma is characterized by high constitutive expression of activating transcription factor 3 (ATF3), which promotes viability of Hodgkin/Reed-Sternberg cells.
High-resolution analysis of 16q22.1 in breast carcinoma using DNA amplifiable probes (multiplex amplifiable probe hybridization technique) and immunohistochemistry.
p107 inhibits G1 to S phase progression by down-regulating expression of the F-box protein Skp2.
The adenovirus E4-6/7 protein directs nuclear localization of E2F-4 via an arginine-rich motif.
Expression of E2F-4 gene in colorectal adenocarcinoma and corresponding covering mucosa: an immunohistochemistry, image analysis, and immunoblot study.
Dingar D, Konecny F, Zou J, Sun X, von Harsdorf R
Journal of molecular and cellular cardiology 2012 Dec;53(6):820-8
Journal of molecular and cellular cardiology 2012 Dec;53(6):820-8
Effects of isotretinoin on spermatogenesis of rats.
Gencoglan G, Tosun M
Cutaneous and ocular toxicology 2011 Mar;30(1):55-60
Cutaneous and ocular toxicology 2011 Mar;30(1):55-60
Classical Hodgkin lymphoma is characterized by high constitutive expression of activating transcription factor 3 (ATF3), which promotes viability of Hodgkin/Reed-Sternberg cells.
Janz M, Hummel M, Truss M, Wollert-Wulf B, Mathas S, Jöhrens K, Hagemeier C, Bommert K, Stein H, Dörken B, Bargou RC
Blood 2006 Mar 15;107(6):2536-9
Blood 2006 Mar 15;107(6):2536-9
High-resolution analysis of 16q22.1 in breast carcinoma using DNA amplifiable probes (multiplex amplifiable probe hybridization technique) and immunohistochemistry.
Rakha EA, Armour JA, Pinder SE, Paish CE, Ellis IO
International journal of cancer 2005 May 1;114(5):720-9
International journal of cancer 2005 May 1;114(5):720-9
p107 inhibits G1 to S phase progression by down-regulating expression of the F-box protein Skp2.
Rodier G, Makris C, Coulombe P, Scime A, Nakayama K, Nakayama KI, Meloche S
The Journal of cell biology 2005 Jan 3;168(1):55-66
The Journal of cell biology 2005 Jan 3;168(1):55-66
The adenovirus E4-6/7 protein directs nuclear localization of E2F-4 via an arginine-rich motif.
Schaley JE, Polonskaia M, Hearing P
Journal of virology 2005 Feb;79(4):2301-8
Journal of virology 2005 Feb;79(4):2301-8
Expression of E2F-4 gene in colorectal adenocarcinoma and corresponding covering mucosa: an immunohistochemistry, image analysis, and immunoblot study.
Mady HH, Hasso S, Melhem MF
Applied immunohistochemistry & molecular morphology : AIMM 2002 Sep;10(3):225-30
Applied immunohistochemistry & molecular morphology : AIMM 2002 Sep;10(3):225-30
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Supportive validation
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- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Formalin-fixed, paraffin-embedded human tonsil stained with E2F-4 antibody using peroxidase-conjugate and AEC chromogen. Note nuclear staining of cells.
- Conjugate
- Biotin