Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 16169-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16169-1-AP, RRID:AB_10733889
- Product name
- SLC30A8/ZNT8-Specific antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated SLC30A8/ZNT8-Specific antibody (Cat. #16169-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Transcriptional responses of four slc30a/znt family members and their roles in Zn homeostatic modulation in yellow catfish Pelteobagrus fulvidraco.
A change in the zinc ion concentration reflects the maturation of insulin-producing cells generated from adipose-derived mesenchymal stem cells.
Highly specific monoclonal antibodies for allosteric inhibition and immunodetection of the human pancreatic zinc transporter ZnT8.
A subclass of serum anti-ZnT8 antibodies directed to the surface of live pancreatic β-cells.
Coupling of Insulin Secretion and Display of a Granule-resident Zinc Transporter ZnT8 on the Surface of Pancreatic Beta Cells.
Lipid-tuned Zinc Transport Activity of Human ZnT8 Protein Correlates with Risk for Type-2 Diabetes.
Erythropoietin Protects Retinal Cells in Diabetic Rats Through Upregulating ZnT8 via Activating ERK Pathway and Inhibiting HIF-1α Expression.
Song CC, Chen GH, Zhong CC, Chen F, Chen SW, Luo Z
Biochimica et biophysica acta. Gene regulatory mechanisms 2021 Aug;1864(8):194723
Biochimica et biophysica acta. Gene regulatory mechanisms 2021 Aug;1864(8):194723
A change in the zinc ion concentration reflects the maturation of insulin-producing cells generated from adipose-derived mesenchymal stem cells.
Ohta S, Ikemoto T, Wada Y, Saito Y, Yamada S, Imura S, Morine Y, Shimada M
Scientific reports 2019 Dec 10;9(1):18731
Scientific reports 2019 Dec 10;9(1):18731
Highly specific monoclonal antibodies for allosteric inhibition and immunodetection of the human pancreatic zinc transporter ZnT8.
Merriman C, Li H, Li H, Fu D
The Journal of biological chemistry 2018 Oct 19;293(42):16206-16216
The Journal of biological chemistry 2018 Oct 19;293(42):16206-16216
A subclass of serum anti-ZnT8 antibodies directed to the surface of live pancreatic β-cells.
Merriman C, Huang Q, Gu W, Yu L, Fu D
The Journal of biological chemistry 2018 Jan 12;293(2):579-587
The Journal of biological chemistry 2018 Jan 12;293(2):579-587
Coupling of Insulin Secretion and Display of a Granule-resident Zinc Transporter ZnT8 on the Surface of Pancreatic Beta Cells.
Huang Q, Merriman C, Zhang H, Fu D
The Journal of biological chemistry 2017 Mar 10;292(10):4034-4043
The Journal of biological chemistry 2017 Mar 10;292(10):4034-4043
Lipid-tuned Zinc Transport Activity of Human ZnT8 Protein Correlates with Risk for Type-2 Diabetes.
Merriman C, Huang Q, Rutter GA, Fu D
The Journal of biological chemistry 2016 Dec 30;291(53):26950-26957
The Journal of biological chemistry 2016 Dec 30;291(53):26950-26957
Erythropoietin Protects Retinal Cells in Diabetic Rats Through Upregulating ZnT8 via Activating ERK Pathway and Inhibiting HIF-1α Expression.
Xu G, Kang D, Zhang C, Lou H, Sun C, Yang Q, Lu L, Xu GT, Zhang J, Wang F
Investigative ophthalmology & visual science 2015 Dec;56(13):8166-78
Investigative ophthalmology & visual science 2015 Dec;56(13):8166-78
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse pancreas tissue were subjected to SDS PAGE followed by western blot with 16169-1-AP(SLC30A8-Specific antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human pancreas using 16169-1-AP(SLC30A8-Specific antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SLC30A8/ZNT8-Specific antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human SLC30A8/ZNT8-Specific. This antibody recognizes human,mouse,rat antigen. The SLC30A8/ZNT8-Specific antibody has been validated for the following applications: ELISA, WB, IHC analysis.