FNab07157

antibody from FineTest Biotech

Targeting: RBL2 p130, Rb2

Western blot

ELISA

Antibody data

Submit

Validation data

Product number: FNab07157 - Provider product page
Provider: FineTest Biotech
Product name: RBL2 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases KMT5B and KMT5C, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation, associates preferentially with E2F5. Binds to cyclins A and E. Binds to and may be involved in the transforming capacity of the adenovirus E1A protein. May act as a tumor suppressor.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: retinoblastoma-like 2(p130)
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

RBL2 protein structure - FNab07157 shown in red.