BS8209

antibody from Bioworld Technology, Inc
Targeting: COIL CLN80, p80-coilin
Provider product page for BS8209
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS8209 - Provider product page
Provider
Bioworld Technology, Inc
Product name
COIL polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human COIL.
Description
Coilin is the primary protein of nuclear coiled (Cajal) bodies. Cajal bodies are small nuclear organelles and contain many proteins involved in RNA transcription and processing. Coilin is a self-associating protein with a nucleolar localization signal. It is essential for the proper formation of Cajal bodies and for the recruitment of snRNP and survival motor neuron (SMN) complex proteins to Cajal bodies. Coilin directly binds SMN proteins in the recruitment process and competes with SmB£ª for SMN interactions. In the developing organism, Cajal bodies play a role in the assembly of the nucleolus. While the N-terminus of coilin contains the self-associating domain, the C-terminus of coilin regulates the number of Cajal bodies present in the cell.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
COIL protein structure - BS8209 shown in red.