DCTN5

This gene encodes a subunit of dynactin, a component of the cytoplasmic dynein motor machinery involved in minus-end-directed transport. The encoded protein is a component of the pointed-end subcomplex and is thought to bind membranous cargo. A pseudogene of this gene is located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]

Description

Dynactin subunit 5

Tissue specificity

Low tissue specificity

Subcell location

Nucleoplasm, Nuclear membrane

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

16 (23641466 - 23677472)

Ensembl ID

ENSG00000166847  (ver. 103.38)

Orthologs

Mouse Dctn5: ENSMUSG00000030868

UniProt

Q9BTE1

neXtProt

NX_Q9BTE1

Human splice variants
Mouse splice variants

Protein structure