CABT-BL7863

antibody from Creative Diagnostics

Targeting: ITGA2B CD41, CD41B, GP2B, PPP1R93

ELISA (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

CABT-BL7863

Provider

Creative Diagnostics

Product name

Anti-ITGA2B Monoclonal antibody, clone NXSfh40

Antibody type

Monoclonal

Description

ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.

Reactivity

Mouse

Host

Rat

Conjugate

Unconjugated

Isotype

IgG