Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- 303718 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#303718, RRID:AB_10899413
- Product name
- PE/Cy7 anti-human CD41
- Antibody type
- Monoclonal
- Antigen
- CD41
- Description
- CD41 is a 125/25 kD α subunit of the gpIIb/IIIa (CD41/CD61) complex. CD41 is a heterodimer composed of a heavy chain (gpIIbα) and light chain (gpIIbβ) linked by a single disulfide bond. It is a member of the integrin family primarily expressed on platelets and megakaryocytes. CD41 has been reported to be involved with platelet aggregation and platelet attachment to the ECM. CD41/CD61 complex acts as the receptor for fibrinogen, fibronectin, Von Willebrand factor, and thrombin.
- Reactivity
- Human, Simian
- Host
- Mouse
- Conjugate
- Infrared dye
- Isotype
- IgG
- Vial size
- 100 tests
- Storage
- The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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Supportive validation
- Submitted by
- BioLegend (provider)
- Main image
- Experimental details
- Human platelets were stained with CD41 (clone HIP8) APC/Cy7 (filled histogram) or mouse IgG1 APC/Cy7 isotype control (open histogram).
- Conjugate
- Near infrared dye