Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 15439-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15439-1-AP, RRID:AB_2224154
- Product name
- AKR1B1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated AKR1B1 antibody (Cat. #15439-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, rat and has been validated for the following applications: IF, WB,ELISA.
- Reactivity
- Human, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Systematic investigation of the pharmacological mechanism for renal protection by the leaves of Eucommia ulmoides Oliver using UPLC-Q-TOF/MS combined with network pharmacology analysis.
WJ-39, an Aldose Reductase Inhibitor, Ameliorates Renal Lesions in Diabetic Nephropathy by Activating Nrf2 Signaling.
Rosmarinic acid exerts a neuroprotective effect on spinal cord injury by suppressing oxidative stress and inflammation via modulating the Nrf2/HO-1 and TLR4/NF-κB pathways.
Seminal plasma of men with severe asthenozoospermia contain exosomes that affect spermatozoa motility and capacitation.
Regulation on SIRT1-PGC-1α/Nrf2 pathway together with selective inhibition of aldose reductase makes compound hr5F a potential agent for the treatment of diabetic complications.
Bioinformatics analysis of proteomics profiles in senescent human primary proximal tubule epithelial cells.
Huang Q, Zhang F, Liu S, Jiang Y, Ouyang D
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Aug;140:111735
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Aug;140:111735
WJ-39, an Aldose Reductase Inhibitor, Ameliorates Renal Lesions in Diabetic Nephropathy by Activating Nrf2 Signaling.
Zhou X, Liu Z, Ying K, Wang H, Liu P, Ji X, Chi T, Zou L, Wang S, He Z
Oxidative medicine and cellular longevity 2020;2020:7950457
Oxidative medicine and cellular longevity 2020;2020:7950457
Rosmarinic acid exerts a neuroprotective effect on spinal cord injury by suppressing oxidative stress and inflammation via modulating the Nrf2/HO-1 and TLR4/NF-κB pathways.
Ma Z, Lu Y, Yang F, Li S, He X, Gao Y, Zhang G, Ren E, Wang Y, Kang X
Toxicology and applied pharmacology 2020 Apr 19;397:115014
Toxicology and applied pharmacology 2020 Apr 19;397:115014
Seminal plasma of men with severe asthenozoospermia contain exosomes that affect spermatozoa motility and capacitation.
Murdica V, Giacomini E, Alteri A, Bartolacci A, Cermisoni GC, Zarovni N, Papaleo E, Montorsi F, Salonia A, Viganò P, Vago R
Fertility and sterility 2019 May;111(5):897-908.e2
Fertility and sterility 2019 May;111(5):897-908.e2
Regulation on SIRT1-PGC-1α/Nrf2 pathway together with selective inhibition of aldose reductase makes compound hr5F a potential agent for the treatment of diabetic complications.
Wang Z, Yuan S, Li Y, Zhang Z, Xiao W, Tang D, Ye K, Liu Z, Wang C, Zheng Y, Nie H, Chen H
Biochemical pharmacology 2018 Apr;150:54-63
Biochemical pharmacology 2018 Apr;150:54-63
Bioinformatics analysis of proteomics profiles in senescent human primary proximal tubule epithelial cells.
Lu Y, Wang J, Dapeng C, Wu D, Cai G, Chen X
BMC nephrology 2016 Apr 1;17:39
BMC nephrology 2016 Apr 1;17:39
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The AKR1B1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human AKR1B1. This antibody recognizes human, mouse, rat antigen. The AKR1B1 antibody has been validated for the following applications: ELISA, WB analysis.