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antibody from Invitrogen Antibodies
Targeting: CYP19A1
ARO, ARO1, aromatase, CPV1, CYAR, CYP19, P-450AROM
Western blot
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations
- Western blot [1]
- Other assay [4]
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- Product number
- PA1-21398 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- Aromatase Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide
- Description
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
- Reactivity
- Human, Mouse, Rat, Bovine, Chicken/Avian, Porcine, Rabbit
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 50 µg
- Concentration
- 0.5 mg/mL
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Submitted references KISS1R and ANKRD31 Cooperate to Enhance Leydig Cell Gene Expression via the Cytoskeletal-Nucleoskeletal Pathway.
High Doses of D-Chiro-Inositol Alone Induce a PCO-Like Syndrome and Other Alterations in Mouse Ovaries.
Role of vaspin in porcine ovary: effect on signaling pathways and steroid synthesis via GRP78 receptor and protein kinase A†.
INSIGHTS ON AROMATASE IMMUNOHISTOCHEMISTRY: VARIATIONS BETWEEN INTRINSIC MOLECULAR SUBTYPES OF BREAST CANCERS.
The role of vaspin in porcine corpus luteum.
Tanshinone IIA attenuates estradiol-induced polycystic ovarian syndrome in mice by ameliorating FSHR expression in the ovary.
Increased expression of aromatase cytochrome P450 enzyme is associated with prolactinoma invasiveness in post-menopausal women.
Developmental programming: Changes in mediators of insulin sensitivity in prenatal bisphenol A-treated female sheep.
Developmental Programming: Impact of Prenatal Testosterone Excess on Steroidal Machinery and Cell Differentiation Markers in Visceral Adipocytes of Female Sheep.
Aromatase enzyme expression in acromegaly and its possible relationship with disease prognosis.
Developmental programming: prenatal steroid excess disrupts key members of intraovarian steroidogenic pathway in sheep.
Pathogen-associated molecular patterns initiate inflammation and perturb the endocrine function of bovine granulosa cells from ovarian dominant follicles via TLR2 and TLR4 pathways.
Ricci G, Guillou F, Catizone A, Mele VG, Moggio M, Chioccarelli T, Diano N, Meccariello R, Pierantoni R, Fasano S, Cobellis G, Chianese R, Manfrevola F
Frontiers in cell and developmental biology 2022;10:877270
Frontiers in cell and developmental biology 2022;10:877270
High Doses of D-Chiro-Inositol Alone Induce a PCO-Like Syndrome and Other Alterations in Mouse Ovaries.
Bevilacqua A, Dragotto J, Lucarelli M, Di Emidio G, Monastra G, Tatone C
International journal of molecular sciences 2021 May 26;22(11)
International journal of molecular sciences 2021 May 26;22(11)
Role of vaspin in porcine ovary: effect on signaling pathways and steroid synthesis via GRP78 receptor and protein kinase A†.
Kurowska P, Mlyczyńska E, Dawid M, Dupont J, Rak A
Biology of reproduction 2020 May 26;102(6):1290-1305
Biology of reproduction 2020 May 26;102(6):1290-1305
INSIGHTS ON AROMATASE IMMUNOHISTOCHEMISTRY: VARIATIONS BETWEEN INTRINSIC MOLECULAR SUBTYPES OF BREAST CANCERS.
Armasu I, Preda C, Ianole V, Mocanu V, Hristov I, Andriescu EC, Cretu-Silivestru I, Vasiliu I, Dascalu CG, Lupascu CD, Crumpei I, Serban DN, Serban IL, Ciobanu Apostol DG
Acta endocrinologica (Bucharest, Romania : 2005) 2020 Jan-Mar;16(1):22-29
Acta endocrinologica (Bucharest, Romania : 2005) 2020 Jan-Mar;16(1):22-29
The role of vaspin in porcine corpus luteum.
Kurowska P, Mlyczyńska E, Dawid M, Grzesiak M, Dupont J, Rak A
The Journal of endocrinology 2020 Dec;247(3):283-294
The Journal of endocrinology 2020 Dec;247(3):283-294
Tanshinone IIA attenuates estradiol-induced polycystic ovarian syndrome in mice by ameliorating FSHR expression in the ovary.
Jin J, Hu QY, Xu WW, Zhu WJ, Liu B, Liu J, Wang W, Zhou HF
Experimental and therapeutic medicine 2019 May;17(5):3501-3508
Experimental and therapeutic medicine 2019 May;17(5):3501-3508
Increased expression of aromatase cytochrome P450 enzyme is associated with prolactinoma invasiveness in post-menopausal women.
Su YX, Du GL, Shen HL, Wang W, Bao JL, Aierken A, Wang BW, Jiang S, Zhu J, Gao XM
The Journal of international medical research 2019 Jul;47(7):3115-3126
The Journal of international medical research 2019 Jul;47(7):3115-3126
Developmental programming: Changes in mediators of insulin sensitivity in prenatal bisphenol A-treated female sheep.
Puttabyatappa M, Martin JD, Andriessen V, Stevenson M, Zeng L, Pennathur S, Padmanabhan V
Reproductive toxicology (Elmsford, N.Y.) 2019 Apr;85:110-122
Reproductive toxicology (Elmsford, N.Y.) 2019 Apr;85:110-122
Developmental Programming: Impact of Prenatal Testosterone Excess on Steroidal Machinery and Cell Differentiation Markers in Visceral Adipocytes of Female Sheep.
Puttabyatappa M, Lu C, Martin JD, Chazenbalk G, Dumesic D, Padmanabhan V
Reproductive sciences (Thousand Oaks, Calif.) 2018 Jul;25(7):1010-1023
Reproductive sciences (Thousand Oaks, Calif.) 2018 Jul;25(7):1010-1023
Aromatase enzyme expression in acromegaly and its possible relationship with disease prognosis.
Selek A, Cetinarslan B, Gurbuz Y, Tarkun I, Canturk Z, Cabuk B
Endocrine 2015 May;49(1):250-7
Endocrine 2015 May;49(1):250-7
Developmental programming: prenatal steroid excess disrupts key members of intraovarian steroidogenic pathway in sheep.
Padmanabhan V, Salvetti NR, Matiller V, Ortega HH
Endocrinology 2014 Sep;155(9):3649-60
Endocrinology 2014 Sep;155(9):3649-60
Pathogen-associated molecular patterns initiate inflammation and perturb the endocrine function of bovine granulosa cells from ovarian dominant follicles via TLR2 and TLR4 pathways.
Price JC, Bromfield JJ, Sheldon IM
Endocrinology 2013 Sep;154(9):3377-86
Endocrinology 2013 Sep;154(9):3377-86
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Western Blot analysis of human brain lysate using Aromatase Polyclonal Antibody (Product # PA1-21398).
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- NULL
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Figure 7 Levels of aromatase in the ovaries of mice at the end of the 21-day treatment. ( A ) Representative Western blot of aromatase in protein extracts from the ovaries of mice under the experimental conditions indicated. ( B ) Densitometric analysis of aromatase/GAPDH. Values represent the mean value +- SD of extracts from three independent experiments. *, difference vs. negative control mice, p < 0.05.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Figure 4 Dose-dependent effect of vaspin added alone (A-C) or in combination with IGF1, or FSH or LH (D-F) on E2 secretion (A, D) and CYP19A1 mRNA (B, E), and protein (C, F) expression. ELISA, real-time PCR, and western blotting experiments were performed independently and repeated five times ( n = 5). Data are plotted as the mean +- SEM. Significance between control and treatments is indicated by * P < 0.05, ** P < 0.01, and *** P < 0.001; or by different letters ( P < 0.05), C: control.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Figure 2. Expression levels of P450AROM, ER-beta, Ki-67, and p53 with respect to menstrual status and tumor invasiveness. Representative immunohistochemical staining for P450AROM (a), ER-beta (b), Ki-67 (c), and p53 (d); e, g, i, and k: respective prolactinoma tissue staining scores in pre- and post-menopausal women; f, h, j, l: respective prolactinoma tissue staining scores in non-invasive and invasive prolactinomas of post-menopausal women. In a-d, magnification x40; open arrows indicate negative immunostaining and solid arrows indicate positive immunostaining. In e-l, error bars indicate standard deviation; * P < 0.05.
