A02627

antibody from Boster Biological Technology

Targeting: MYO6 DFNA22, DFNB37, KIAA0389

Western blot (Data presented on provider website)

Antibody Data

Product number

A02627

Provider

Boster Biological Technology

Product name

Anti-Myosin-6 MYO6 Antibody

Antibody type

Polyclonal

Description

Polyclonal antibody for MYO6 detection. Host: Rabbit.Size: 100μL. Tested applications: WB. Reactive species: Human. MYO6 information: Molecular Weight: 149691 MW; Subcellular Localization: Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Golgi apparatus . Nucleus. Cytoplasm, perinuclear region. Membrane, clathrin-coated pit. Cell projection, ruffle membrane; Peripheral membrane protein. Also present in endocyctic vesicles, and membrane ruffles. Translocates from membrane ruffles, endocytic vesicles and cytoplasm to Golgi apparatus, perinuclear membrane and nucleus through induction by p53 and p53-induced DNA damage. Recruited into membrane ruffles from cell surface by EGF- stimulation. Colocalizes with DAB2 in clathrin-coated pits/vesicles. Colocalizes with OPTN at the Golgi complex and in vesicular structures close to the plasma membrane (By similarity); Tissue Specificity: Expressed in most tissues examined including heart, brain, placenta, pancreas, spleen, thymus, prostate, testis, ovary, small intestine and colon. Highest levels in brain, pancreas, testis and small intestine. Also expressed in fetal brain and cochlea. Isoform 1 and isoform 2, containing the small insert, and isoform 4, containing neither insert, are expressed in unpolarized epithelial cells.

Reactivity

Human

Host

Rabbit

Vial size

100μL

Concentration

25 mg/mL by Refractometry

Storage

At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquoted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.