Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [1]
- Other assay [1]
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Validation data
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- Product number
- PA5-25050 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- Tubulin beta-2C Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide
- Description
- This antibody is predicted to react with bovine, chicken, canine, hamster, mouse, porcine, rat and Xenopus based on sequence homology.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 400 µL
- Concentration
- 0.5 mg/mL
- Storage
- -20° C, Avoid Freeze/Thaw Cycles
Submitted references Tubulin Beta 2C Chain (TBB2C), a Potential Marker of Ovarian Cancer, an Insight from Ovarian Cancer Proteome Profile.
Therapeutic efficacy of a novel βIII/βIV-tubulin inhibitor (VERU-111) in pancreatic cancer.
Noreen S, Akhtar S, Batool T, Gardner QA, Akhtar MW
ACS omega 2021 Apr 27;6(16):10506-10514
ACS omega 2021 Apr 27;6(16):10506-10514
Therapeutic efficacy of a novel βIII/βIV-tubulin inhibitor (VERU-111) in pancreatic cancer.
Kashyap VK, Wang Q, Setua S, Nagesh PKB, Chauhan N, Kumari S, Chowdhury P, Miller DD, Yallapu MM, Li W, Jaggi M, Hafeez BB, Chauhan SC
Journal of experimental & clinical cancer research : CR 2019 Jan 23;38(1):29
Journal of experimental & clinical cancer research : CR 2019 Jan 23;38(1):29
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Western blot analysis using a TUBB2C polyclonal antibody (Product # PA5-25050) in HeLa, MDA-MB435, MDA-MB231, HepG2 cell lysates (35 µg per lane).
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Western blot analysis using a TUBB2C polyclonal antibody (Product # PA5-25050) in HeLa, MDA-MB435, MDA-MB231, HepG2 cell lysates (35 µg per lane).
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemistry analysis in formalin-fixed, paraffin-embedded human brain tissue using a TUBB2C polyclonal antibody (Product # PA5-25050), followed by HRP-conjugated secondary antibody and DAB staining.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Figure 3 Validation analysis of the candidate proteins. Immunoblots of TBB2C and VIM. (A) Relative expression of TBB2C in different OC stages compared to benign controls and healthy subjects (ns, non significant; * p -value, 0.01; *** p -value, 0.0004; **** p -value < 0.0001). (B) ROC curve displaying TBB2C sensitivity to distinguish OC from benign controls and healthy subjects, and benign controls from healthy subjects (C).