306401

antibody from BioLegend
Targeting: FASLG APT1LG1, CD178, FasL, TNFSF6
Provider product page for 306401
Immunocytochemistry
Immunoprecipitation
Flow cytometry

Antibody data

Product number
306401 - Provider product page
Provider
BioLegend
Product name
Purified anti-human CD178 (Fas-L)
Antibody type
Monoclonal
Antigen
L5178Y mouse T lymphoma cells expressing recombinant human FasL
Description
CD178 is a 38-42 kD type II glycoprotein also known as Fas ligand and CD95L. CD178 belongs to the TNF superfamily and is expressed on activated T lymphocytes, NK cells, monocytes, and granulocytes. CD178 is also expressed on parenchymal cells of the retina and cornea, retinal pigment epithelial cells, and testis. The extracellular region of FasL can be cleaved by matrix metalloproteinases (MMPs) to give rise to a 26 kD soluble protein. CD178 binds to CD95, a member of the TNFR superfamily, to induce apoptosis. CD95/CD95L interactions play an important role in the maintenance of peripheral tolerance and survival.
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Isotype
IgG
Vial size
25 µg
Concentration
0.5 mg/ml
Storage
The antibody solution should be stored undiluted at 4°C.
FASLG protein structure - 306401 shown in red.