FNab01467

antibody from FineTest Biotech
Targeting: CD33 FLJ00391, p67, SIGLEC-3, SIGLEC3
Provider product page for FNab01467
Western blot
ELISA
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
FNab01467 - Provider product page
Provider
FineTest Biotech
Product name
CD33 antibody
Antibody type
Polyclonal
Antigen
Recombinant protein fragment
Description
Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia(in vitro).
Reactivity
Human
Host
Rabbit
Conjugate
Unconjugated
Antigen sequence
CD33 molecule
Epitope
IgG
Isotype
IgG
Vial size
100¦Ìg
Concentration
Immunogen affinity purified
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
CD33 protein structure - FNab01467 shown in red.