SEC24A

The protein encoded by this gene belongs to a family of proteins that are homologous to yeast Sec24. This protein is a component of coat protein II (COPII)-coated vesicles that mediate protein transport from the endoplasmic reticulum. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the golgi complex. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

Description

SEC24 homolog A, COPII coat complex component

Tissue specificity

Low tissue specificity

Subcell location

Nucleoli fibrillar center, Vesicles

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

5 (134648785 - 134727909)

Ensembl ID

ENSG00000113615  (ver. 103.38)

Orthologs

Mouse Sec24a: ENSMUSG00000036391

UniProt

O95486

neXtProt

NX_O95486

Human splice variants
Mouse splice variants

Protein structure