BS60770

antibody from Bioworld Technology, Inc
Targeting: SLC4A7 NBC3, SBC2, SLC4A6
Provider product page for BS60770

Antibody data

Product number
BS60770 - Provider product page
Provider
Bioworld Technology, Inc
Product name
SLC4A7 polyclonal antibody
Antibody type
Polyclonal
Antigen
A synthetic peptide corresponding to residues in Human SLC4A7.
Description
SLC4A7 (solute carrier family 4 member 7), also known as sodium bicarbonate cotransporter 3, is a 1,214 amino acid multi-pass membrane protein that mediates the movement of sodium and bicarbonate across the cell membrane. Studies in mice have shown that hydrogen ion disposal mediated by SLC4A7 is essential for auditory and visual systems, therefore, defects in the gene encoding SLC4A7 may result in the human manifestation of Usher syndrome, a leading cause of deafblindness. With highest expression in spleen and testis, SLC4A7 is also expressed in a variety of other tissues, including brain, skeletal muscle and heart. Due to its critical role in intracellular pH regulation, SLC4A7 is notably affected by hypoxic states during which protein levels are decreased, presumably for reduction of energy consumption. There are five isoforms of SLC4A7 that exist as a result of alternative splicing events.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
SLC4A7 protein structure - BS60770 shown in red.