BS6177

antibody from Bioworld Technology, Inc
Targeting: BCL10 c-E10, CARMEN, CIPER, CLAP, mE10
Provider product page for BS6177
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS6177 - Provider product page
Provider
Bioworld Technology, Inc
Product name
Bcl 10 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human Bcl-10.
Description
Bcl10, also designated CIPER, c-CARMEN and mE10, was first identified as a gene truncated or mutated in MALT B cell lymphomas and other tumor types. Bcl10 is homologous to the equine herpesvirus-2 E10 gene and, like E10, it contains an N-terminal caspase recruitment domain (CARD). Expression of Bcl10 has been shown to induce NFKB activation in a NIK-dependent pathway, and research indicates that the CARD domain is essential for this activation; although in a separate study, Bcl10 by itself did not induce JNK or NFkB activation.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
BCL10 protein structure - BS6177 shown in red.