Explore
Validate
Learn
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- PAB4537 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB4537, RRID:AB_1579140
- Product name
- PRKCE polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of PRKCE.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Activated PKC{delta} and PKC{epsilon} inhibit epithelial chloride secretion response to cAMP via inducing internalization of the Na+-K+-2Cl- cotransporter NKCC1.
Preservation of base-line hemodynamic function and loss of inducible cardioprotection in adult mice lacking protein kinase C epsilon.
Induction of neurites by the regulatory domains of PKCdelta and epsilon is counteracted by PKC catalytic activity and by the RhoA pathway.
Protein kinase Cepsilon interacts with Bax and promotes survival of human prostate cancer cells.
Tang J, Bouyer P, Mykoniatis A, Buschmann M, Matlin KS, Matthews JB
The Journal of biological chemistry 2010 Oct 29;285(44):34072-85
The Journal of biological chemistry 2010 Oct 29;285(44):34072-85
Preservation of base-line hemodynamic function and loss of inducible cardioprotection in adult mice lacking protein kinase C epsilon.
Gray MO, Zhou HZ, Schafhalter-Zoppoth I, Zhu P, Mochly-Rosen D, Messing RO
The Journal of biological chemistry 2004 Jan 30;279(5):3596-604
The Journal of biological chemistry 2004 Jan 30;279(5):3596-604
Induction of neurites by the regulatory domains of PKCdelta and epsilon is counteracted by PKC catalytic activity and by the RhoA pathway.
Ling M, Trollér U, Zeidman R, Lundberg C, Larsson C
Experimental cell research 2004 Jan 1;292(1):135-50
Experimental cell research 2004 Jan 1;292(1):135-50
Protein kinase Cepsilon interacts with Bax and promotes survival of human prostate cancer cells.
McJilton MA, Van Sikes C, Wescott GG, Wu D, Foreman TL, Gregory CW, Weidner DA, Harris Ford O, Morgan Lasater A, Mohler JL, Terrian DM
Oncogene 2003 Sep 11;22(39):7958-68
Oncogene 2003 Sep 11;22(39):7958-68
No comments: Submit comment
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of PRKCE polyclonal antibody (Cat # PAB4537) in placenta lysate . PRKCE (Arrow) was detected using PRKCE polyclonal antibody (Cat # PAB4537) . Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence .
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of PRKCE (arrow) using rabbit PRKCE polyclonal antibody (Cat # PAB4537). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PRKCE gene (Lane 2) (Origene Technologies).
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with PRKCE polyclonal antibody (Cat # PAB4537) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining . This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated . HC = hepatocarcinoma .
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
