Ab111533

antibody from Aladdin Scientific Corporation

Targeting: MAPK9 JNK2, p54a, PRKM9, SAPK

Western blot (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

Ab111533

Provider

Aladdin Scientific Corporation

Product name

Recombinant JNK2 Antibody

Antibody type

Recombinant

Description

Rabbit anti Human JNK2 Antibody, Recombinant (R02-9H4), could be used for WB, IHC and so on.Application:WB: 1/500-1/1000 IHC: 1/50-1/100FunctionResponds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells. JNK2 isoforms display different binding patterns: alpha-1 and alpha-2 preferentially bind to c-Jun, whereas beta-1 and beta-2 bind to ATF2. However, there is no correlation between binding and phosphorylation, which is achieved at about the same efficiency by all isoforms. JUNB is not a substrate for JNK2 alpha-2, and JUND binds only weakly to it.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Antigen sequence

AA 361-374


Antibody clone number

R02-9H4

Vial size

100μl,10μl,1ml,50μl

Concentration

0,3 mg/ml

Storage

Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.