Tissue expression
Cell line expression
Protein structure
LARS1
Leucyl-tRNA synthetase 1FLJ10595, FLJ21788, HSPC192, LARS, LEUS, RNTLS
This gene encodes a cytosolic leucine-tRNA synthetase, a member of the class I aminoacyl-tRNA synthetase family. The encoded enzyme catalyzes the ATP-dependent ligation of L-leucine to tRNA(Leu). It is found in the cytoplasm as part of a multisynthetase complex and interacts with the arginine tRNA synthetase through its C-terminal domain. A mutation in this gene was found in affected individuals with infantile liver failure syndrome 1. Alternatively spliced transcript variants of this gene have been observed. [provided by RefSeq, Dec 2015]
Top validated antibodies |
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Proteintech Group | ![]() |
9 references | Polyclonal |
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Invitrogen Antibodies | ![]() |
Polyclonal |
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NovoPro Bioscience Inc. | ![]() |
Polyclonal |
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FineTest Biotech | ![]() |
Polyclonal |
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Biorbyt | ![]() |
Polyclonal |
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