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LearnPAB2886
antibody from Abnova Corporation
Targeting: LARS1
FLJ10595, FLJ21788, HSPC192, LARS, LEUS, RNTLS
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- PAB2886 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB2886, RRID:AB_1576760
- Product name
- LARS polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of LARS.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references A single residue in leucyl-tRNA synthetase affecting amino acid specificity and tRNA aminoacylation.
The C-terminal appended domain of human cytosolic leucyl-tRNA synthetase is indispensable in its interaction with arginyl-tRNA synthetase in the multi-tRNA synthetase complex.
Assignment of a human genetic locus to chromosome 5 which corrects the heat sensitive lesion associated with reduced leucyl-tRNA synthetase activity in ts025Cl Chinese hamster cells.
Lue SW, Kelley SO
Biochemistry 2007 Apr 17;46(15):4466-72
Biochemistry 2007 Apr 17;46(15):4466-72
The C-terminal appended domain of human cytosolic leucyl-tRNA synthetase is indispensable in its interaction with arginyl-tRNA synthetase in the multi-tRNA synthetase complex.
Ling C, Yao YN, Zheng YG, Wei H, Wang L, Wu XF, Wang ED
The Journal of biological chemistry 2005 Oct 14;280(41):34755-63
The Journal of biological chemistry 2005 Oct 14;280(41):34755-63
Assignment of a human genetic locus to chromosome 5 which corrects the heat sensitive lesion associated with reduced leucyl-tRNA synthetase activity in ts025Cl Chinese hamster cells.
Giles RE, Shimizu N, Ruddle FH
Somatic cell genetics 1980 Sep;6(5):667-687
Somatic cell genetics 1980 Sep;6(5):667-687
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of LARS polyclonal antibody (Cat # PAB2886) in 293 cell line lysates (35 ug/lane). LARS (arrow) was detected using the purified polyclonal antibody.
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human prostate carcinomareacted with LARS polyclonal antibody (Cat # PAB2886), which was peroxidase-conjugated to the secondary antibody, followed by AEC staining.This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
