FNab10720

antibody from FineTest Biotech

Targeting: F2RL1 GPR11, PAR2

ELISA

Immunohistochemistry

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Validation data

Product number: FNab10720 - Provider product page
Provider: FineTest Biotech
Product name: PAR2 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Proteinase-activated receptors(PARs) are G protein-coupled receptors activated through cleavage of their N-termini by mainly serine proteases. The family of PARs include four members: PAR1, PAR2, PAR3 and PAR4. PAR2, also known as F2RL1, is expressed in epithelial cells(e.g., lung, gastrointestinal tract), endothelial cells, smooth muscle cells, fibroblasts, nerves, and some immune and inflammatory cells. PAR2 knockout mice and PAR2 agonists and antagonists have implicated PAR2 as a promising target in inflammatory conditions; respiratory, gastrointestinal, metabolic, cardiovascular, and neurological dysfunction; and cancers.(PMID:23895492)
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: coagulation factor II(thrombin) rec eptor-like 1
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

F2RL1 protein structure - FNab10720 shown in red.