CABT-B070

antibody from Creative Diagnostics

Targeting: EXOC6 DKFZp761I2124, EXOC6A, FLJ1125, MGC33397, SEC15L, SEC15L1, Sec15p

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Antibody Data

Product number

CABT-B070

Provider

Creative Diagnostics

Product name

Anti-EXOC6 monoclonal antibody, clone 26T3H7

Antibody type

Monoclonal

Description

Exocyst complex (also known as the sec6/8 complex) is a multimeric complex that has been implicated to play a role in exocytosis. This complex is conserved from yeast to mammals and is composed of eight subunits (Sec3, Sec5, Sec6, Sec8, Sec10, Sec15, Exo70, and Exo84). In the budding yeast Saccharomyces cerevisiae, mutations in these complex subunits promote cytoplasmic accumulation of secretory vesicles and affects polarized growth. In cultured Drosophila and mammlian cells, disruption of exocyst subunit function has been found to decrease neurite outgrowth and Golgi-to-plasma membrane vesicle trafficking. Furthermore, a delay in neuronal induction was observed in mouse embryos with deletion of the sec8 gene, suggesting that the exocyst complex may play a role in cell differentiation and polarized growth.

Reactivity

Mouse, Rat

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

26T3H7

Vial size

100_g

Concentration

1mg/ml

Storage

Store at 4°C