Tissue expression
Cell line expression
Protein structure
TMEM158
Transmembrane protein 158p40BBp, RIS1
Constitutive activation of the Ras pathway triggers an irreversible proliferation arrest reminiscent of replicative senescence. Transcription of this gene is upregulated in response to activation of the Ras pathway, but not under other conditions that induce senescence. The encoded protein is similar to a rat cell surface receptor proposed to function in a neuronal survival pathway. An allelic polymorphism in this gene results in both functional and non-functional (frameshifted) alleles; the reference genome represents the functional allele. [provided by RefSeq, Jul 2015]
Top validated antibodies |
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antibodies-online | ABIN1386582 | Polyclonal |
WB
ICC
IHC
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LSBio | LS-C157938 | Polyclonal |
WB
|
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Invitrogen Antibodies | PA5-100204 | Polyclonal |
WB
ICC |
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NovoPro Bioscience Inc. | 117810 | Polyclonal |
WB
EL |
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Bioss | bs-11770R | Polyclonal |
WB
ICC
IHC
|
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