abx012102

antibody from Abbexa

Targeting: LRP5 BMND1, EVR1, EVR4, HBM, LR3, LRP7, OPPG, OPS, OPTA1, VBCH2

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

abx012102

Provider

Abbexa

Product name

Low Density Lipoprotein Receptor Related Protein 5 (LRP5) Antibody

Antibody type

Monoclonal

Description

This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

1 mg/ml

Storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.