Tissue expression
Cell line expression
Protein structure
SACM1L
SAC1 like phosphatidylinositide phosphataseKIAA0851, SAC1
This gene encodes an integral membrane protein, which is localized to the endoplasmic reticulum, and functions as a phosphoinositide phosphatase that hydrolyzes phosphatidylinositol 3-phosphate, phosphatidylinositol 4-phosphate, and phosphatidylinositol 3,5-bisphosphate. Deletion of this gene in mouse results in preimplantation lethality. Other studies suggest that this gene is also involved in the organization of golgi membranes and mitotic spindles. Alternatively spliced transcript variants have been found for this gene. A C-terminally extended isoform is also predicted to be produced by the use of an alternative in-frame, downstream translation termination codon via a stop codon readthrough mechanism. [provided by RefSeq, Dec 2017]
Top validated antibodies |
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Proteintech Group | 13033-1-AP | 18 references | Polyclonal |
WB
EL
ICC
IP
IHC
|
|
Invitrogen Antibodies | 13033-1-AP | Polyclonal |
WB
ICC
IP
IHC
OA
|
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FineTest Biotech | FNab07576 | Polyclonal |
WB
EL
ICC
IP
IHC
|
||
Biorbyt | orb630938 | Polyclonal |
WB
EL
ICC
IP
IHC
|
||
NovoPro Bioscience Inc. | 115041 | Polyclonal |
WB
EL
IP
IHC |
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