Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Immunohistochemistry [3]
- Flow cytometry [2]
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Validation data
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- Product number
- DDX0480P-100 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal TLR8 Antibody
- Antibody type
- Monoclonal
- Description
- Ion exchange chromatography.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 0.5 mg/ml
- Storage
- Store at -20C. Avoid freeze-thaw cycles.
Submitted references Smoking decreases the response of human lung macrophages to double-stranded RNA by reducing TLR3 expression.
UNC93B1 physically associates with human TLR8 and regulates TLR8-mediated signaling.
Toll-like receptor signaling pathway in chronic lymphocytic leukemia: distinct gene expression profiles of potential pathogenic significance in specific subsets of patients.
Todt JC, Freeman CM, Brown JP, Sonstein J, Ames TM, McCubbrey AL, Martinez FJ, Chensue SW, Beck JM, Curtis JL
Respiratory research 2013 Mar 9;14:33
Respiratory research 2013 Mar 9;14:33
UNC93B1 physically associates with human TLR8 and regulates TLR8-mediated signaling.
Itoh H, Tatematsu M, Watanabe A, Iwano K, Funami K, Seya T, Matsumoto M
PloS one 2011;6(12):e28500
PloS one 2011;6(12):e28500
Toll-like receptor signaling pathway in chronic lymphocytic leukemia: distinct gene expression profiles of potential pathogenic significance in specific subsets of patients.
Arvaniti E, Ntoufa S, Papakonstantinou N, Touloumenidou T, Laoutaris N, Anagnostopoulos A, Lamnissou K, Caligaris-Cappio F, Stamatopoulos K, Ghia P, Muzio M, Belessi C
Haematologica 2011 Nov;96(11):1644-52
Haematologica 2011 Nov;96(11):1644-52
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Frozen: TLR8 Antibody (303F1.14) [DDX0480P-100] - Analysis using the Alexa Fluor (R) 488 conjugate of DDX0480P-100. Staining of human tonsil frozen section.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Frozen: TLR8 Antibody (303F1.14) [DDX0480P-100] - IF staining of human tonsil cryosection with 303F1-A488
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry: TLR8 Antibody (303F1.14) [DDX0480P-100] - IHC staining of moDCs (GMCSF+IL4 day6) with 303F1
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow Cytometry: TLR8 Antibody (303F1.14) [DDX0480P-100] - Facs staining of TLR8- transfected 293T cells with 303F1
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow Cytometry: TLR8 Antibody (303F1.14) [DDX0480P-100] - TLR8 expression on B-CLL (Arvaniti E et al, 2011)